TY - JOUR AU - Cheng-Sánchez, Iván AU - Carrillo, Paloma AU - Sánchez-Ruiz, Antonio AU - Martínez-Poveda, Beatriz AU - Quesada, Ana R AU - Medina, Miguel A AU - López-Romero, Juan M AU - Sarabia, Francisco PY - 2018 DO - 10.1021/acs.joc.7b02988 UR - http://hdl.handle.net/10668/12374 T2 - The Journal of organic chemistry AB - New synthetic strategies directed toward the novel cyclopeptides solomonamides have been explored utilizing an olefin metathesis as the key reaction. In the various strategies investigated, we worked on minimally oxidized systems, and the olefin... LA - en KW - Antineoplastic Agents KW - Cell Line, Tumor KW - Cell Proliferation KW - Cyclization KW - Dose-Response Relationship, Drug KW - Drug Screening Assays, Antitumor KW - Humans KW - Molecular Conformation KW - Peptides, Cyclic KW - Structure-Activity Relationship TI - Exploring the Ring-Closing Metathesis for the Construction of the Solomonamide Macrocyclic Core: Identification of Bioactive Precursors. TY - research article VL - 83 ER -