RT Journal Article
T1 Quantification of pulmonary regurgitation in patients with repaired Tetralogy of Fallot by 2D phase-contrast MRI: Differences between the standard method of velocity averaging and a pixel-wise analysis.
A1 Sotelo, Julio
A1 Bächler, Pablo
A1 Urbina, Jesús
A1 Crelier, Gerard
A1 Toro, Lida
A1 Ferreiro, Myriam
A1 Valverde, Israel
A1 Andia, Marcelo
A1 Tejos, Cristian
A1 Irarrazaval, Pablo
A1 Uribe, Sergio
K1 Tetralogy of Fallot
K1 magnetic resonance imaging
K1 pulmonary valve insufficiency
K1 two-dimensional flow
AB To compare the values of pulmonary regurgitation in patients with repaired Tetralogy of Fallot quantified from two-dimensional phase-contrast data, by using a new pixel-wise analysis and the standard velocity-averaging method. Quantitative in silico and in vivo analysis. Hospital Sótero del Río. The magnetic resonance images were acquired using a Philips Achieva 1.5T scanner. Twenty-five patients with repaired Tetralogy of Fallot who underwent cardiovascular magnetic resonance imaging requested by their referring physicians were included in this study. Using a computational fluid dynamics simulation, we validated our pixel-wise method, quantifying the error of our method in comparison with the standard method. The patients underwent a standard two-dimensional phase-contrast magnetic resonance imaging acquisition for quantifying pulmonary artery flow. Pulmonary regurgitation fraction was estimated by using our pixel-wise and the standard method. The two-dimensional flow profiles were inspected looking for simultaneous antegrade and retrograde flows in the same cardiac phase. Statistical analysis was performed with t-test for related samples, Bland-Altman plots, and Pearson correlation coefficient. Estimation of pulmonary regurgitation fraction using the pixel-wise analysis revealed higher values compared with the standard method (39 ± 16% vs. 30 ± 22%, p-value  Quantification of pulmonary regurgitation fraction in patients with repaired Tetralogy of Fallot through a pixel-wise analysis yields higher values of pulmonary regurgitation compared with the standard velocity-averaging method.
SN 2048-0040
YR 2017
FD 2017-09-21
LK https://hdl.handle.net/10668/27320
UL https://hdl.handle.net/10668/27320
LA en
DS RISalud
RD Apr 17, 2025