TY - JOUR AU - Alvarez-Cubero, Maria Jesus AU - Martinez-Gonzalez, Luis Javier AU - Saiz, Maria AU - Carmona-Saez, Pedro AU - Alvarez, Juan Carlos AU - Pascual-Geler, Manrique AU - Lorente, Jose Antonio AU - Cozar, Jose Manuel PY - 2015 DO - 10.1038/emm.2015.43 SN - 1226-3613 UR - http://hdl.handle.net/10668/2058 T2 - Experimental & molecular medicine AB - The aim of this study was to analyze the use of 12 single-nucleotide polymorphisms in genes ELAC2, RNASEL and MSR1 as biomarkers for prostate cancer (PCa) detection and progression, as well as perform a genetic classification of high-risk patients. A... LA - en PB - Nature Publishing Group KW - Biopsia KW - Estudios de seguimiento KW - Frecuencia de los genes KW - Humanos KW - Masculino KW - Clasificación del tumor KW - Nucleótidos KW - Polimorfismo de nucleótido simple KW - Antígeno prostático específico KW - Neoplasias de la próstata KW - Análisis de regresión KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Clinical Laboratory Techniques::Cytological Techniques::Cytodiagnosis::Biopsy KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cohort Studies::Longitudinal... KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Gene Frequency KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans KW - Medical Subject Headings::Check Tags::Male KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Prognosis::Neoplasm Grading KW - Medical Subject Headings::Chemicals and Drugs::Carbohydrates::Glycosides::Nucleotides KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Variation::Polymorphism, Genetic::Polymorphism, Single Nucleotide KW - Medical Subject Headings::Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Hydrolases::Peptide Hydrolases::Endopeptidases::Serine Endopeptidases::Kallikreins::Prostate-Specific Antigen KW - Medical Subject Headings::Diseases::Neoplasms::Neoplasms by Site::Urogenital Neoplasms::Genital Neoplasms, Male::Prostatic Neoplasms KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Regression Analysis TI - Prognostic role of genetic biomarkers in clinical progression of prostate cancer. TY - research article ER -