RT Journal Article
T1 Transcatheter aortic valve implantation in very elderly patients: immediate results and medium term follow-up.
A1 Pascual, Isaac
A1 Muñoz-García, Antonio J
A1 López-Otero, Diego
A1 Avanzas, Pablo
A1 Jiménez-Navarro, Manuel F
A1 Cid-Alvarez, Belén
A1 Valle, Raquel del
A1 Alonso-Briales, Juan H
A1 Ocaranza-Sánchez, Raimundo
A1 Hernández, José M
A1 Trillo-Nouche, Ramiro
A1 Morís, César
K1 Aortic stenosis
K1 High surgical risk
K1 Transcatheter aortic valve
K1 Very elderly patients
K1 Reemplazo de la válvula aórtica transcatéter
K1 Humanos
K1 Anciano
K1 Estenosis de la válvula aórtica
K1 Tasa de supervivencia
K1 Hemorragia
AB OBJECTIVETo evaluate immediate transcatheter aortic valve implantation (TAVI) results and medium-term follow-up in very elderly patients with severe and symptomatic aortic stenosis (AS).METHODSThis multicenter, observational and prospective study was carried out in three hospitals. We included consecutive very elderly (> 85 years) patients with severe AS treated by TAVI. The primary endpoint was to evaluate death rates from any cause at two years.RESULTSThe study included 160 consecutive patients with a mean age of 87 ± 2.1 years (range from 85 to 94 years) and a mean logistic EuroSCORE of 18.8% ± 11.2% with 57 (35.6%) patients scoring ≥ 20%. Procedural success rate was 97.5%, with 25 (15.6%) patients experiencing acute complications with major bleeding (the most frequent). Global mortality rate during hospitalization was 8.8% (n = 14) and 30-day mortality rate was 10% (n = 16). Median follow up period was 252.24 ± 232.17 days. During the follow-up period, 28 (17.5%) patients died (17 of them due to cardiac causes). The estimated two year overall and cardiac survival rates using the Kaplan-Meier method were 71% and 86.4%, respectively. Cox proportional hazard regression showed that the variable EuroSCORE ≥ 20 was the unique variable associated with overall mortality.CONCLUSIONSTAVI is safe and effective in a selected population of very elderly patients. Our findings support the adoption of this new procedure in this complex group of patients.
PB Institute of Geriatric Cardiology, Chinese PLA General Hospital
YR 2015
FD 2015-07-04
LK http://hdl.handle.net/10668/2052
UL http://hdl.handle.net/10668/2052
LA en
NO Pascual I, Muñoz-García AJ, López-Otero D, Avanzas P, Jiménez-Navarro MF, Cid-Álvarez B, et al. Transcatheter aortic valve implantation in very elderly patients: immediate results and medium term follow-up. J Geriatr Cardiol. 2015; 12(4):340-5
NO Journal Article;
DS RISalud
RD Apr 18, 2025