%0 Journal Article
%A Pascual, Isaac
%A Muñoz-García, Antonio J
%A López-Otero, Diego
%A Avanzas, Pablo
%A Jiménez-Navarro, Manuel F
%A Cid-Alvarez, Belén
%A Valle, Raquel del
%A Alonso-Briales, Juan H
%A Ocaranza-Sánchez, Raimundo
%A Hernández, José M
%A Trillo-Nouche, Ramiro
%A Morís, César
%T Transcatheter aortic valve implantation in very elderly patients: immediate results and medium term follow-up.
%D 2015
%U http://hdl.handle.net/10668/2052
%X OBJECTIVETo evaluate immediate transcatheter aortic valve implantation (TAVI) results and medium-term follow-up in very elderly patients with severe and symptomatic aortic stenosis (AS).METHODSThis multicenter, observational and prospective study was carried out in three hospitals. We included consecutive very elderly (> 85 years) patients with severe AS treated by TAVI. The primary endpoint was to evaluate death rates from any cause at two years.RESULTSThe study included 160 consecutive patients with a mean age of 87 ± 2.1 years (range from 85 to 94 years) and a mean logistic EuroSCORE of 18.8% ± 11.2% with 57 (35.6%) patients scoring ≥ 20%. Procedural success rate was 97.5%, with 25 (15.6%) patients experiencing acute complications with major bleeding (the most frequent). Global mortality rate during hospitalization was 8.8% (n = 14) and 30-day mortality rate was 10% (n = 16). Median follow up period was 252.24 ± 232.17 days. During the follow-up period, 28 (17.5%) patients died (17 of them due to cardiac causes). The estimated two year overall and cardiac survival rates using the Kaplan-Meier method were 71% and 86.4%, respectively. Cox proportional hazard regression showed that the variable EuroSCORE ≥ 20 was the unique variable associated with overall mortality.CONCLUSIONSTAVI is safe and effective in a selected population of very elderly patients. Our findings support the adoption of this new procedure in this complex group of patients.
%K Aortic stenosis
%K High surgical risk
%K Transcatheter aortic valve
%K Very elderly patients
%K Reemplazo de la válvula aórtica transcatéter
%K Humanos
%K Anciano
%K Estenosis de la válvula aórtica
%K Tasa de supervivencia
%K Hemorragia
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