TY - JOUR AU - Gerdes, Patricia AU - Lim, Sue Mei AU - Ewing, Adam D AU - Larcombe, Michael R AU - Chan, Dorothy AU - Sanchez-Luque, Francisco J AU - Walker, Lucinda AU - Carleton, Alexander L AU - James, Cini AU - Knaupp, Anja S AU - Carreira, Patricia E AU - Nefzger, Christian M AU - Lister, Ryan AU - Richardson, Sandra R AU - Polo, Jose M AU - Faulkner, Geoffrey J PY - 2022 DO - 10.1038/s41467-022-35180-x UR - http://hdl.handle.net/10668/19551 T2 - Nature communications AB - Induced pluripotent stem cells (iPSCs) can in principle differentiate into any cell of the body, and have revolutionized biomedical research and regenerative medicine. Unlike their human counterparts, mouse iPSCs (miPSCs) are reported to silence... LA - en KW - Humans KW - Mice KW - Animals KW - Induced Pluripotent Stem Cells KW - Retroelements KW - DNA Transposable Elements KW - Mutation KW - Long Interspersed Nucleotide Elements TI - Retrotransposon instability dominates the acquired mutation landscape of mouse induced pluripotent stem cells. TY - research article VL - 13 ER -