TY  - JOUR
AU  - Copmans, Daniëlle
AU  - Rateb, Mostafa
AU  - Tabudravu, Jioji N
AU  - Pérez-Bonilla, Mercedes
AU  - Dirkx, Nina
AU  - Vallorani, Riccardo
AU  - Diaz, Caridad
AU  - Pérez Del Palacio, José
AU  - Smith, Alan J
AU  - Ebel, Rainer
AU  - Reyes, Fernando
AU  - Jaspars, Marcel
AU  - de Witte, Peter A M
PY  - 2018
DO  - 10.1021/acschemneuro.8b00060
UR  - http://hdl.handle.net/10668/12371
T2  - ACS chemical neuroscience
AB  - In search for novel antiseizure drugs (ASDs), the European FP7-funded PharmaSea project used zebrafish embryos and larvae as a drug discovery platform to screen marine natural products to identify promising antiseizure hits in vivo for further...
LA  - en
KW  - Aspergillus fumigatus
KW  - Epilepsy
KW  - antiseizure drug discovery
KW  - azaspirofuran A
KW  - marine drug discovery
KW  - pseurotin A2
KW  - Animals
KW  - Anticonvulsants
KW  - Aspergillus fumigatus
KW  - Brain
KW  - Cell Line
KW  - Drug Discovery
KW  - Drug Resistant Epilepsy
KW  - Electric Stimulation
KW  - Humans
KW  - Indian Ocean
KW  - Lactams
KW  - Male
KW  - Mice
KW  - Molecular Structure
KW  - Pyrrolidinones
KW  - Random Allocation
KW  - Seizures
KW  - Spiro Compounds
KW  - Zebrafish
TI  - Zebrafish-Based Discovery of Antiseizure Compounds from the Red Sea: Pseurotin A2 and Azaspirofuran A.
TY  - research article
VL  - 9
ER  -