TY - JOUR AU - Baeza, Victor AU - Cifuentes, Manuel AU - Martínez, Fernando AU - Ramírez, Eder AU - Nualart, Francisco AU - Ferrada, Luciano AU - Oviedo, María José AU - De Lima, Isabelle AU - Troncoso, Ninoschka AU - Saldivia, Natalia AU - Salazar, Katterine PY - 2021 DO - 10.1038/s41598-021-97948-3 UR - http://hdl.handle.net/10668/4196 T2 - Scientific Reports AB - Ependymal cells have multiple apical cilia that line the ventricular surfaces and the central canal of spinal cord. In cancer, the loss of ependymal cell polarity promotes the formation of different types of tumors, such as supratentorial anaplastic... LA - en PB - Springer Nature KW - Caspase-3 KW - Adherens junctions KW - Gliosis KW - Cadherins KW - Ependymoma KW - Adenovirus KW - Cells KW - Caspasa 3 KW - Uniones adherentes KW - Cadherinas KW - Ependimoma KW - Adenoviridae KW - Células KW - Medical Subject Headings::Anatomy::Cells::Cellular Structures::Cell Membrane::Cell Membrane Structures::Intercellular Junctions::Adherens Junctions KW - Medical Subject Headings::Organisms::Eukaryota::Animals KW - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Adhesion KW - Medical Subject Headings::Anatomy::Cells::Cells, Cultured KW - Medical Subject Headings::Anatomy::Nervous System::Central Nervous System::Brain::Cerebral Ventricles::Ependyma KW - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Nerve Tissue Proteins KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Rats::Rats, Sprague-Dawley KW - Medical Subject Headings::Persons::Persons::Age Groups::Adult KW - Medical Subject Headings::Persons::Persons::Age Groups::Child KW - Medical Subject Headings::Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Hydrolases::Peptide Hydrolases::Cysteine Proteases::Cysteine Endopeptidases::Caspases::Caspases, Effector::Caspase 3 KW - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Polarity KW - Medical Subject Headings::Diseases::Pathological Conditions, Signs and Symptoms::Pathologic Processes::Gliosis KW - Medical Subject Headings::Diseases::Nervous System Diseases::Central Nervous System Diseases::Brain Diseases::Hydrocephalus KW - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Glycoproteins::Membrane Glycoproteins::Cell Adhesion Molecules::Cadherins KW - Medical Subject Headings::Diseases::Neoplasms::Neoplasms by Histologic Type::Neoplasms, Germ Cell and Embryonal::Neuroectodermal Tumors::Neoplasms, Neuroepithelial::Glioma::Ependymoma KW - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Differentiation KW - Medical Subject Headings::Anatomy::Nervous System::Central Nervous System::Spinal Cord KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Diagnostic Imaging::Microscopy::Microscopy, Electron::Microscopy, Electron, Transmission KW - Medical Subject Headings::Organisms::Viruses::DNA Viruses::Adenoviridae KW - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Death KW - Medical Subject Headings::Anatomy::Cells::Cellular Structures::Intracellular Space::Cytoplasm KW - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Cytoskeletal Proteins::Catenins KW - Medical Subject Headings::Anatomy::Cells TI - IIIG9 inhibition in adult ependymal cells changes adherens junctions structure and induces cellular detachment TY - research article ER -