TY  - JOUR
AU  - Gonzalez-Cano, Rafael
AU  - Montilla-García, Ángeles
AU  - Perazzoli, Gloria
AU  - Torres, Jesús M.
AU  - Cañizares, Francisco J.
AU  - Fernández-Segura, Eduardo
AU  - Costigan, Michael
AU  - Baeyens, José M.
AU  - Cobos, Enrique J.
PY  - 2021
DO  - 10.3389/fphar.2020.613068
UR  - http://hdl.handle.net/10668/4002
T2  - Frontiers in Pharmacology
AB  - Both TRPA1 and purinergic P2X receptors have been proposed as potential targets for the treatment of visceral pain. We found that the intracolonic administration of a low dose mustard oil (0.5%), a well-known TRPA1 agonist, produced nociceptive...
LA  - en
PB  - Frontiers Research Foundation
KW  - Mustard oil
KW  - Visceral pain
KW  - Resiniferatoxin
KW  - TRPA1
KW  - TRPV1
KW  - P2X
KW  - Dolor visceral
KW  - Hyperalgesia
KW  - Hiperalgesia
KW  - Nociceptors
KW  - Nociceptores
KW  - Abdominal wall
KW  - Pared abdominal
KW  - Spinal cord
KW  - Médula espinal
KW  - Medical Subject Headings::Diseases::Nervous System Diseases::Neurologic Manifestations::Sensation Disorders::Somatosensory Disorders::Hyperalgesia
KW  - Medical Subject Headings::Anatomy::Cells::Neurons::Neurons, Afferent::Sensory Receptor Cells::Nociceptors
KW  - Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Specialty Uses of Chemicals::Irritants
KW  - Medical Subject Headings::Diseases::Pathological Conditions, Signs and Symptoms::Signs and Symptoms::Neurologic Manifestations::Pain::Nociceptive Pain::Visceral Pain
KW  - Medical Subject Headings::Psychiatry and Psychology::Psychological Phenomena and Processes::Mental Processes::Perception::Pain Perception::Nociception
KW  - Medical Subject Headings::Anatomy::Body Regions::Torso::Abdomen::Abdominal Wall
KW  - Medical Subject Headings::Chemicals and Drugs::Heterocyclic Compounds::Heterocyclic Compounds, 2-Ring::Purines::Purine Nucleotides::Adenine Nucleotides::Adenosine Triphosphate
KW  - Medical Subject Headings::Anatomy::Nervous System::Central Nervous System::Spinal Cord
KW  - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Carrier Proteins::Membrane Transport Proteins::Ion Channels::Ligand-Gated Ion Channels::Receptors, Purinergic P2X
KW  - Medical Subject Headings::Anatomy::Tissues::Epithelium
TI  - Intracolonic Mustard Oil Induces Visceral Pain in Mice by TRPA1-Dependent and -Independent Mechanisms: Role of Tissue Injury and P2X Receptors
TY  - research article
ER  -