RT Journal Article
T1 Pyoderma gangrenosum-like necrotizing panniculitis associated with Imatinib: A case report.
A1 Hernández, Jorge
A1 Sanz, Alicia
A1 Isla-Tejera, Beatriz
A1 Ruano, Juan
K1 Imatinib
K1 necrotizing panniculitis
K1 pyoderma gangrenosum- like
AB Imatinib mesylate is a small tyrosine kinase inhibitor that targets BCR-ABL, ckit and platelet-derived growth factor receptor. It is prescribed by hematologists for chronic myeloid leukemia and acute lymphoblastic leukemia and by oncologists for Gastrointestinal Stromal Tumors (GIST). Cutaneous reactions to Imatinib are common but their incidence and severity widely varies between patients. A self-limited skin rash is the most common adverse effect but there have been reported cases of patients with maculopapular rash, pigmentary changes, superficial edema and rarer and clinically distinctive features such as lichenoid reactions or psoriasis. We here describe for the first time a case of pyoderma gangrenosum-like necrotizing panniculitis, a rare dermatological condition, after initiating therapy with Imatinib.
SN 2036-7392
YR 2020
FD 2020-07-08
LK https://hdl.handle.net/10668/24753
UL https://hdl.handle.net/10668/24753
LA en
DS RISalud
RD Apr 17, 2025