RT Journal Article
T1 Melatonin-doped polymeric nanoparticles induce high crystalline apatite formation in root dentin
A1 Toledano-Osorio, Manuel
A1 Aguilera, Fatima S.
A1 Munoz-Soto, Esther
A1 Osorio, Estrella
A1 Toledano, Manuel
A1 Escames, Germaine
A1 Medina-Castillo, Antonio L.
A1 Osorio, Maria T.
A1 Lopez-Lopez, Modesto T.
A1 Vallecillo-Rivas, Marta
A1 Osorio, Raquel
K1 Apatite
K1 Dentin
K1 Hardness
K1 Melatonin
K1 Polymeric nanoparticles
K1 Remineralization
K1 Transmission electron microscopy
K1 X-ray diffraction
K1 Oxidative stress
K1 Carious dentin
K1 Organic matrix
K1 Hydroxyapatite
K1 Bone
K1 Cements
K1 Remineralization
K1 Mineralization
K1 Interface
K1 Texture
AB Objective. To investigate the effect of novel polymeric nanoparticles (NPs) doped with melatonin (ML) on nano-hardness, crystallinity and ultrastructure of the formed hydroxyapatite after endodontic treatment. Methods. Undoped-NPs and ML-doped NPs (ML-NPs) were tested at radicular dentin, after 24 h and 6 m. A control group without NPs was included. Radicular cervical and apical dentin surfaces were studied by nano-hardness measurements, X-ray diffraction and transmission electron microscopy. Mean and standard deviation were analyzed by ANOVA and StudentNewman-Keuls multiple comparisons (p
PB Elsevier sci ltd
SN 0109-5641
YR 2021
FD 2021-11-03
LK http://hdl.handle.net/10668/18759
UL http://hdl.handle.net/10668/18759
LA en
DS RISalud
RD Apr 10, 2025