%0 Journal Article
%A Toledano-Osorio, Manuel
%A Aguilera, Fatima S.
%A Munoz-Soto, Esther
%A Osorio, Estrella
%A Toledano, Manuel
%A Escames, Germaine
%A Medina-Castillo, Antonio L.
%A Osorio, Maria T.
%A Lopez-Lopez, Modesto T.
%A Vallecillo-Rivas, Marta
%A Osorio, Raquel
%T Melatonin-doped polymeric nanoparticles induce high crystalline apatite formation in root dentin
%D 2021
%@ 0109-5641
%U http://hdl.handle.net/10668/18759
%X Objective. To investigate the effect of novel polymeric nanoparticles (NPs) doped with melatonin (ML) on nano-hardness, crystallinity and ultrastructure of the formed hydroxyapatite after endodontic treatment. Methods. Undoped-NPs and ML-doped NPs (ML-NPs) were tested at radicular dentin, after 24 h and 6 m. A control group without NPs was included. Radicular cervical and apical dentin surfaces were studied by nano-hardness measurements, X-ray diffraction and transmission electron microscopy. Mean and standard deviation were analyzed by ANOVA and StudentNewman-Keuls multiple comparisons (p
%K Apatite
%K Dentin
%K Hardness
%K Melatonin
%K Polymeric nanoparticles
%K Remineralization
%K Transmission electron microscopy
%K X-ray diffraction
%K Oxidative stress
%K Carious dentin
%K Organic matrix
%K Hydroxyapatite
%K Bone
%K Cements
%K Remineralization
%K Mineralization
%K Interface
%K Texture
%~