%0 Journal Article %A Marth, Christian %A Tarnawski, Rafal %A Tyulyandina, Alexandra %A Pignata, Sandro %A Gilbert, Lucy %A Kaen, Diego %A Rubio, M. Jesus %A Frentzas, Sophia %A Beiner, Mario %A Magallanes-Maciel, Manuel %A Farrelly, Laura %A Choi, Chel Hun %A Berger, Regina %A Lee, Christine %A Vulsteke, Christof %A Hasegawa, Kosei %A Braicu, Elena Ioanna %A Wu, Xiaohua %A McKenzie, Jodi %A Lee, John J. %A Makker, Vicky %T Phase 3, randomized, open-label study of pembrolizumab plus lenvatinib versus chemotherapy for first-line treatment of advanced or recurrent endometrial cancer: ENGOT-en9/LEAP-001 %D 2021 %@ 1048-891X %U https://hdl.handle.net/10668/25441 %X Background Pembrolizumab plus lenvatinib is a novel combination with promising efficacy in patients with advanced and recurrent endometrial cancer. This combination demonstrated high objective response rates in a single-arm phase 1b/2 trial of lenvatinib plus pembrolizumab in patients with advanced endometrial cancer (KEYNOTE-146/Study 111) after %~