TY - JOUR AU - Relaño-Rodríguez, Ignacio AU - Juárez-Sánchez, Raquel AU - Pavicic, Carolina AU - Muñoz, Eduardo AU - Muñoz-Fernández, Maria Ángeles PY - 2019 DO - 10.1186/s12951-019-0500-4 UR - http://hdl.handle.net/10668/3128 T2 - Journal of Nanobiotechnology AB - Background: The major obstacle impeding human immunodeficiency virus-1 (HIV-1) eradication in antiretroviral treatment (ART) treated HIV-1 subjects is the establishment of long-lived latently infected resting CD4+ T cells. Due to the fact that no drug... LA - en KW - Nanomedicine KW - Dendrimers KW - HIV-1 latency KW - Latency reversal agents KW - Nanomedicina KW - Dendrímeros KW - VIH-1 KW - Latencia del virus KW - Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Physiological Effects of Drugs::Immunologic Factors::Adjuvants, Immunologic KW - Medical Subject Headings::Chemicals and Drugs::Organic Chemicals::Lactones::Macrolides::Bryostatins KW - Medical Subject Headings::Anatomy::Cells::Cells, Cultured::Cell Line KW - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Survival KW - Medical Subject Headings::Chemicals and Drugs::Macromolecular Substances::Polymers::Dendrimers KW - Medical Subject Headings::Chemicals and Drugs::Polycyclic Compounds::Macrocyclic Compounds::Peptides, Cyclic::Depsipeptides KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Drug Therapy::Drug Therapy, Combination KW - Medical Subject Headings::Diseases::Immune System Diseases::Immunologic Deficiency Syndromes::HIV Infections KW - Medical Subject Headings::Organisms::Viruses::Vertebrate Viruses::RNA Viruses::Retroviridae::Lentivirus::Lentiviruses, Primate::HIV::HIV-1 KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans KW - Medical Subject Headings::Anatomy::Cells::Blood Cells::Leukocytes::Leukocytes, Mononuclear::Lymphocytes KW - Medical Subject Headings::Anatomy::Hemic and Immune Systems::Immune System::Mononuclear Phagocyte System::Monocytes KW - Medical Subject Headings::Phenomena and Processes::Chemical Phenomena::Physicochemical Phenomena::Particle Size KW - Medical Subject Headings::Chemicals and Drugs::Macromolecular Substances::Polymers KW - Medical Subject Headings::Chemicals and Drugs::Organic Chemicals::Organosilicon Compounds::Silanes KW - Medical Subject Headings::Phenomena and Processes::Chemical Phenomena::Physicochemical Phenomena::Surface Properties KW - Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Therapeutic Uses::Anti-Infective Agents::Antiviral Agents::Anti-Retroviral Agents::Anti-HIV Agents TI - Polyanionic carbosilane dendrimers as a new adjuvant in combination with latency reversal agents for HIV treatment TY - research article ER -