TY - JOUR AU - Jaén, Rafael I AU - Val-Blasco, Almudena AU - Prieto, Patricia AU - Gil-Fernández, Marta AU - Smani, Tarik AU - López-Sendón, José Luis AU - Delgado, Carmen AU - Boscá, Lisardo AU - Fernández-Velasco, María PY - 2020 DO - 10.1016/j.jacbts.2020.03.015 UR - https://hdl.handle.net/10668/26653 T2 - JACC. Basic to translational science AB - Cardiovascular diseases (CVDs) are the leading cause of death in the industrialized world. Most CVDs are associated with increased inflammation that arises mainly from innate immune system activation related to cardiac damage. Sustained activation of... LA - en KW - AMI, acute myocardial infarction KW - CARD, caspase activation and recruitment domain KW - CVD, cardiovascular disease KW - Ca2+, calcium ion KW - DAMPs, danger-associated molecular patterns KW - DAP, D-glutamyl-meso-diaminopimelic acid KW - ER, endoplasmic reticulum KW - HF, heart failure KW - I/R, ischemia/reperfusion KW - IL, interleukin KW - MAPK, mitogen-activated protein kinase KW - NF-κB, nuclear factor κ-light-chain-enhancer of activated B cells KW - NLR, nucleotide-binding oligomerization domain-like receptors KW - NLRP, nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain-containing receptor KW - NLRP3 KW - NOD, Nucleotide-binding oligomerization domain-containing protein KW - NOD1 KW - PAMP, pathogen-associated molecular pattern KW - ROS, reactive oxygen species KW - SR, sarcoplasmic reticulum KW - TLR, toll-like receptor KW - cardiovascular disease KW - innate immune system KW - nucleotide-binding oligomerization domain-like receptors KW - toll-like receptors TI - Innate Immune Receptors, Key Actors in Cardiovascular Diseases. TY - research article VL - 5 ER -