TY  - JOUR
AU  - Velasco, Ana
AU  - Tokat, Fatma
AU  - Bonde, Jesper
AU  - Trim, Nicola
AU  - Bauer, Elisabeth
AU  - Meeney, Adam
AU  - de Leng, Wendy
AU  - Chong, George
AU  - Dalstein, Véronique
AU  - Kis, Lorand L
AU  - Lorentzen, Jon A
AU  - Tomić, Snjezana
AU  - Thwaites, Keeley
AU  - Putzová, Martina
AU  - Birnbaum, Astrid
AU  - Qazi, Romena
AU  - Primmer, Vanessa
AU  - Dockhorn-Dworniczak, Barbara
AU  - Hernández-Losa, Javier
AU  - Soares, Fernando A
AU  - Gertler, Asaf A
AU  - Kalman, Michal
AU  - Wong, Chris
AU  - Carraro, Dirce M
AU  - Sousa, Ana C
AU  - Reis, Rui M
AU  - Fox, Stephen B
AU  - Fassan, Matteo
AU  - Brevet, Marie
AU  - Merkelbach-Bruse, Sabine
AU  - Colling, Richard
AU  - Soilleux, Elizabeth
AU  - Teo, Ryan Yee Wei
AU  - D'Haene, Nicky
AU  - Nolet, Serge
AU  - Ristimäki, Ari
AU  - Väisänen, Timo
AU  - Chapusot, Caroline
AU  - Soruri, Afsaneh
AU  - Unger, Tina
AU  - Wecgowiec, Johanna
AU  - Biscuola, Michele
AU  - Frattini, Milo
AU  - Long, Anna
AU  - Campregher, Paulo V
AU  - Matias-Guiu, Xavier
PY  - 2020
DO  - 10.1007/s00428-020-02962-x
UR  - http://hdl.handle.net/10668/16579
T2  - Virchows Archiv : an international journal of pathology
AB  - Microsatellite instability (MSI) is present in 15-20% of primary colorectal cancers. MSI status is assessed to detect Lynch syndrome, guide adjuvant chemotherapy, determine prognosis, and use as a companion test for checkpoint blockade inhibitors....
LA  - en
KW  - Colorectal cancer
KW  - FFPE clinical tissue samples
KW  - Idylla™ MSI assay
KW  - Microsatellite instability
KW  - Multi-center study
KW  - Automation, Laboratory
KW  - Biomarkers, Tumor
KW  - Colorectal Neoplasms
KW  - DNA Mutational Analysis
KW  - Fixatives
KW  - Formaldehyde
KW  - Humans
KW  - Immunohistochemistry
KW  - Microsatellite Instability
KW  - Mutation
KW  - Paraffin Embedding
KW  - Predictive Value of Tests
KW  - Reproducibility of Results
KW  - Tissue Fixation
TI  - Multi-center real-world comparison of the fully automated Idylla™ microsatellite instability assay with routine molecular methods and immunohistochemistry on formalin-fixed paraffin-embedded tissue of colorectal cancer.
TY  - research article
VL  - 478
ER  -