RT Journal Article T1 Factors associated with unreported tuberculosis cases in Spanish hospitals. A1 Morales-García, Concepción A1 Rodrigo, Teresa A1 García-Clemente, Marta M A1 Muñoz, Ana A1 Bermúdez, Pilar A1 Casas, Francisco A1 Somoza, María A1 Milá, Celia A1 Penas, Antón A1 Hidalgo, Carmen A1 Casals, Martí A1 Caylá, Joan A K1 Notifications K1 Under-reporting K1 Reporting K1 Tuberculosis K1 Spain K1 Intervalos de confianza K1 Trazado de contacto K1 Demografía K1 Grupo de ascendencia continental europea K1 Instituciones de Salud K1 Humanos K1 Modelos logísticos K1 Oportunidad relativa K1 Salud pública K1 Estudios retrospectivos K1 España K1 Tuberculosis AB BACKGROUNDUnder-reporting of tuberculosis (TB) cases complicates disease control, hinders contact tracing and alters the accuracy of epidemiological data, including disease burden. The objective of the present study is to evaluate the proportion of unreported TB cases in Spanish healthcare facilities and to identify the associated factors.METHODSA multi-center retrospective study design was employed. The study included TB cases diagnosed in 16 facilities during 2011-2012. These cases were compared to those reported to the corresponding public health departments. Demographic, microbiological and clinical data were analyzed to determine the factors associated with unreported cases. Associated factors were analyzed on a bivariate level using the x(2) test and on a multivariate level using a logistic regression. Odds ratios (OR) and 95 % confidence intervals (CI) were calculated.RESULTSOf the 592 TB cases included in the study, 85 (14.4 %) were not reported. The percentage of unreported cases per healthcare center ranged from 0-45.2 %. The following variables were associated to under-reporting at a multivariate level: smear-negative TB (OR = 1.87; CI:1.07-3.28), extrapulmonary disease (OR = 2.07; CI:1.05-4.09) and retired patients (OR = 3.04; CI:1.29-7.18). A nurse case manager was present in all of the centers with 100 % reporting. The percentage of reported cases among the smear-positive cases was 9.4 % and 19.4 % (p = 0.001) among the rest of the study population. Smear-positive TB was no associated to under-reporting.CONCLUSIONSIt is important that TB Control Programs encourage thorough case reporting to improve disease control, contact tracing and accuracy of epidemiological data. The help from a TB nurse case manager could improve the rate of under-reporting. PB BioMed Central YR 2015 FD 2015-07-29 LK http://hdl.handle.net/10668/2372 UL http://hdl.handle.net/10668/2372 LA en NO Morales-García C, Rodrigo T, García-Clemente MM, Muñoz A, Bermúdez P, Casas F, et al. Factors associated with unreported tuberculosis cases in Spanish hospitals. BMC Infect. Dis.2015; 15:295 NO Journal Article; Research Support, Non-U.S. Gov't; DS RISalud RD Apr 11, 2025