%0 Journal Article
%A Valle-Hita, Cristina
%A Diaz-Lopez, Andres
%A Becerra-Tomas, Nerea
%A Martinez-Gonzalez, Miguel A
%A Garcia, Veronica Ruiz
%A Corella, Dolores
%A Goday, Albert
%A Martinez, J Alfredo
%A Alonso-Gómez, Angel M
%A Wärnberg, Julia
%A Vioque, Jesus
%A Romaguera, Dora
%A Lopez-Miranda, Jose
%A Estruch, Ramon
%A Tinahones, Francisco J
%A Lapetra, Jose
%A Serra-Majem, Luis
%A Cano-Ibañez, Naomi
%A Tur, Josep A
%A Rubin-Garcia, Maria
%A Pinto, Xavier
%A Delgado-Rodriguez, Miguel
%A Matia-Martin, Pilar
%A Vidal, Josep
%A Fontao, Sebastian Mas
%A Daimiel, Lidia
%A Ros, Emilio
%A Toledo, Estefania
%A Sorli, Jose V
%A Roca, C
%A Abete, Iztiar
%A Moreno-Rodriguez, Anai
%A Crespo-Oliva, Edelys
%A Candela-Garcia, Inmaculada
%A Morey, Marga
%A Garcia-Rios, Antonio
%A Casas, Rosa
%A Fernandez-Garcia, Jose Carlos
%A Santos-Lozano, Jose Manuel
%A Diez-Espino, Javier
%A Ortega-Azorin, Carolina
%A Comas, M
%A Zulet, M Angeles
%A Sorto-Sanchez, Carolina
%A Ruiz-Canela, Miguel
%A Fito, Montse
%A Salas-Salvado, Jordi
%A Babio, Nancy
%T Prospective associations between a priori dietary patterns adherence and kidney function in an elderly Mediterranean population at high cardiovascular risk.
%D 2022
%U http://hdl.handle.net/10668/19908
%X To assess the association between three different a priori dietary patterns adherence (17-item energy reduced-Mediterranean Diet (MedDiet), Trichopoulou-MedDiet and Dietary Approach to Stop Hypertension (DASH)), as well as the Protein Diet Score and kidney function decline after one year of follow-up in elderly individuals with overweight/obesity and metabolic syndrome (MetS). We prospectively analyzed 5675 participants (55-75 years) from the PREDIMED-Plus study. At baseline and at one year, we evaluated the creatinine-based estimated glomerular filtration rate (eGFR) and food-frequency questionnaires-derived dietary scores. Associations between four categories (decrease/maintenance and tertiles of increase) of each dietary pattern and changes in eGFR (ml/min/1.73m2) or ≥ 10% eGFR decline were assessed by fitting multivariable linear or logistic regression models, as appropriate. Participants in the highest tertile of increase in 17-item erMedDiet Score showed higher upward changes in eGFR (β: 1.87 ml/min/1.73m2; 95% CI: 1.00-2.73) and had lower odds of ≥ 10% eGFR decline (OR: 0.62; 95% CI: 0.47-0.82) compared to individuals in the decrease/maintenance category, while Trichopoulou-MedDiet and DASH Scores were not associated with any renal outcomes. Those in the highest tertile of increase in Protein Diet Score had greater downward changes in eGFR (β: - 0.87 ml/min/1.73m2; 95% CI: - 1.73 to - 0.01) and 32% higher odds of eGFR decline (OR: 1.32; 95% CI: 1.00-1.75). Among elderly individuals with overweight/obesity and MetS, only higher upward change in the 17-item erMedDiet score adherence was associated with better kidney function after one year. However, increasing Protein Diet Score appeared to have an adverse impact on kidney health.
%K DASH diet
%K Dietary patterns
%K Glomerular filtration rate
%K Kidney function
%K Mediterranean diet
%K Protein diet score
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