TY - JOUR AU - Paz-Ares, Luis AU - Kim, Tae Min AU - Vicente, David AU - Felip, Enriqueta AU - Lee, Dae Ho AU - Lee, Ki Hyeong AU - Lin, Chia-Chi AU - Flor, Maria Jose AU - Di Nicola, Massimo AU - Alvarez, Rosa Maria AU - Dussault, Isabelle AU - Helwig, Christoph AU - Ojalvo, Laureen S AU - Gulley, James L AU - Cho, Byoung Chul PY - 2020 DO - 10.1016/j.jtho.2020.03.003 UR - http://hdl.handle.net/10668/15241 T2 - Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer AB - The safety and efficacy of bintrafusp alfa, a first-in-class bifunctional fusion protein composed of the extracellular domain of the transforming growth factor β (TGF-β) receptor II (a TGF-β "trap") fused to a human immunoglobulin G1 antibody blocking... LA - en KW - Bintrafusp alfa KW - M7824 KW - NSCLC KW - PD-L1 KW - TGF-β KW - Antibodies, Monoclonal KW - B7-H1 Antigen KW - Carcinoma, Non-Small-Cell Lung KW - Humans KW - Lung Neoplasms KW - Transforming Growth Factor beta TI - Bintrafusp Alfa, a Bifunctional Fusion Protein Targeting TGF-β and PD-L1, in Second-Line Treatment of Patients With NSCLC: Results From an Expansion Cohort of a Phase 1 Trial. TY - research article VL - 15 ER -