RT Journal Article
T1 Clinic-epidemiologic study of human infection by Granada virus, a new phlebovirus within the sandfly fever Naples serocomplex.
A1 Navarro-Marí, José María
A1 Gómez-Camarasa, Cristina
A1 Pérez-Ruiz, Mercedes
A1 Sanbonmatsu-Gámez, Sara
A1 Pedrosa-Corral, Irene
A1 Jiménez-Valera, María
K1 Immunoglobulina G
K1 Immunoglobulina M
K1 Anticuerpos víricos
K1 Fiebre por Flebótomos
K1 Phlebovirus
K1 Psychodidae
K1 Virus de Nápoles de la Fiebre de la Mosca de los Arenales
K1 España
K1 Estudios Seroepidemiológicos
K1 Andalucia
AB Granada virus (GRV), a new phlebovirus within the Naples serocomplex, has been recently described in phlebotomine sandflies from Spain. The presence of anti-GRV immunoglobulin G (IgG) antibodies was investigated by indirect fluorescence assay (IFA) and neutralization test (NT) in 920 serum samples from the Granada population. By IFA, an overall GRV seroprevalence of 15.8% (N = 145) was observed, significantly increasing up to 65 years. NT was positive in 18% of anti-GRV IFA-positive samples. IgG antibodies against Toscana virus (TOSV), a hyperendemic phlebovirus within Granada province, were detected in 40% of anti-GRV-positive cases. Anti-GRV IgM antibodies were detected in 36 (6.6%) of 547 acute-phase serum samples from individuals with febrile illness, exanthema, and/or acute respiratory infection. All positives were anti-TOSV IgM-negative. GRV may infect humans, with most cases being asymptomatic. The codetection of anti-GRV and anti-TOSV IgG antibodies could be attributable to cross-reactivity or exposure to the same transmission vector.
PB American Society of Tropical Medicine and Hygiene
SN 0002-9637
YR 2013
FD 2013-05
LK http://hdl.handle.net/10668/1624
UL http://hdl.handle.net/10668/1624
LA en
NO Navarro-Marí JM, Gómez-Camarasa C, Pérez-Ruiz M, Sanbonmatsu-Gámez S, Pedrosa-Corral I, Jiménez-Valera M. Clinic-epidemiologic study of human infection by Granada virus, a new phlebovirus within the sandfly fever Naples serocomplex. Am. J. Trop. Med. Hyg.. 2013                         ; 88(5):1003-6
NO Journal Article; Research Support, Non-U.S. Gov't;
DS RISalud
RD Apr 9, 2025