TY  - JOUR
AU  - Dhingani, Neel
AU  - Guo, Conghui
AU  - Pan, Jie
AU  - Li, Qi
AU  - Warner, Neil
AU  - Jardine, Sasha
AU  - Leung, Gabriella
AU  - Kotlarz, Daniel
AU  - Gonzaga-Jauregui, Claudia
AU  - Klein, Christoph
AU  - Snapper, Scott B.
AU  - Navas-López, Víctor Manuel
AU  - Muise, Aleixo M.
PY  - 2020
DO  - 10.1038/s41598-020-73482-6
UR  - http://hdl.handle.net/10668/3886
T2  - Scientific Reports
AB  - Very early onset inflammatory bowel disease (VEOIBD) denotes children with onset of IBD before six years of age. A number of monogenic disorders are associated with VEOIBD including tetratricopeptide repeat domain 7A (TTC7A) deficiency....
LA  - en
PB  - Springer Nature
KW  - Child
KW  - Amino acid sequence
KW  - Inflammatory bowel diseases
KW  - Protein binding
KW  - Ubiquitin-protein ligases
KW  - Colitis
KW  - Niño
KW  - Secuencia de aminoácidos
KW  - Enfermedades inflamatorias del intestino
KW  - Unión proteica
KW  - Ubiquitina-proteína ligasas
KW  - Medical Subject Headings::Health Care::Health Care Quality, Access, and Evaluation::Quality of Health Care::Epidemiologic Factors::Age Factors::Age of Onset
KW  - Medical Subject Headings::Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::Molecular Structure::Amino Acid Sequence
KW  - Medical Subject Headings::Persons::Persons::Age Groups::Child::Child, Preschool
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
KW  - Medical Subject Headings::Diseases::Digestive System Diseases::Gastrointestinal Diseases::Intestinal Diseases::Inflammatory Bowel Diseases
KW  - Medical Subject Headings::Check Tags::Male
KW  - Medical Subject Headings::Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::Biochemical Processes::Protein Binding
KW  - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins
KW  - Sequence Homology, Amino Acid
KW  - Medical Subject Headings::Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::Biochemical Processes::Signal Transduction
KW  - Medical Subject Headings::Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Ligases::Ubiquitin-Protein Ligase Complexes::Ubiquitin-Protein Ligases
KW  - Medical Subject Headings::Diseases::Digestive System Diseases::Gastrointestinal Diseases::Intestinal Diseases::Colonic Diseases::Colitis
TI  - The E3 ubiquitin ligase UBR5 interacts with TTC7A and may be associated with very early onset inflammatory bowel disease
TY  - research article
ER  -