TY - JOUR AU - Acosta-Herrera, Marialbert AU - Kerick, Martin AU - Lopéz-Isac, Elena AU - Assassi, Shervin AU - Beretta, Lorenzo AU - Simeón-Aznar, Carmen Pilar AU - Ortego-Centeno, Norberto AU - International SSc Group AU - Proudman, Susanna M AU - Australian Scleroderma Interest Group (ASIG) AU - Hunzelmann, Nicolas AU - Moroncini, Gianluca AU - de Vries-Bouwstra, Jeska K AU - Orozco, Gisela AU - Barton, Anne AU - Herrick, Ariane L AU - Terao, Chikashi AU - Allanore, Yannick AU - Brown, Matthew A AU - Radstake, Timothy Rdj AU - Fonseca, Carmen AU - Denton, Christopher P AU - Mayes, Maureen D AU - Martin, Javier PY - 2021 DO - 10.1136/annrheumdis-2021-219884 UR - http://hdl.handle.net/10668/17969 T2 - Annals of the rheumatic diseases AB - The greatest genetic effect reported for systemic sclerosis (SSc) lies in the major histocompatibility complex (MHC) locus. Leveraging the largest SSc genome-wide association study, we aimed to fine-map this region to identify novel human leucocyte... LA - en KW - autoantibodies KW - genetic KW - immune complex diseases KW - polymorphism KW - systemic sclerosis KW - Alleles KW - Genetic Predisposition to Disease KW - Genome-Wide Association Study KW - HLA-DRB1 Chains KW - Humans KW - Major Histocompatibility Complex KW - Scleroderma, Systemic TI - Comprehensive analysis of the major histocompatibility complex in systemic sclerosis identifies differential HLA associations by clinical and serological subtypes. TY - research article VL - 80 ER -