RT Journal Article
T1 Basic Quality Controls Used in Skin Tissue Engineering.
A1 Linares-Gonzalez, Laura
A1 Rodenas-Herranz, Teresa
A1 Campos, Fernando
A1 Ruiz-Villaverde, Ricardo
A1 Carriel, Víctor
K1 biochemical methods
K1 biomechanical evaluation
K1 histological techniques
K1 quality control
K1 skin tissue engineering
AB Reconstruction of skin defects is often a challenging effort due to the currently limited reconstructive options. In this sense, tissue engineering has emerged as a possible alternative to replace or repair diseased or damaged tissues from the patient's own cells. A substantial number of tissue-engineered skin substitutes (TESSs) have been conceived and evaluated in vitro and in vivo showing promising results in the preclinical stage. However, only a few constructs have been used in the clinic. The lack of standardization in evaluation methods employed may in part be responsible for this discrepancy. This review covers the most well-known and up-to-date methods for evaluating the optimization of new TESSs and orientative guidelines for the evaluation of TESSs are proposed.
SN 2075-1729
YR 2021
FD 2021-09-30
LK https://hdl.handle.net/10668/25991
UL https://hdl.handle.net/10668/25991
LA en
DS RISalud
RD Apr 12, 2025