%0 Journal Article
%A Linares-Gonzalez, Laura
%A Rodenas-Herranz, Teresa
%A Campos, Fernando
%A Ruiz-Villaverde, Ricardo
%A Carriel, Víctor
%T Basic Quality Controls Used in Skin Tissue Engineering.
%D 2021
%@ 2075-1729
%U https://hdl.handle.net/10668/25991
%X Reconstruction of skin defects is often a challenging effort due to the currently limited reconstructive options. In this sense, tissue engineering has emerged as a possible alternative to replace or repair diseased or damaged tissues from the patient's own cells. A substantial number of tissue-engineered skin substitutes (TESSs) have been conceived and evaluated in vitro and in vivo showing promising results in the preclinical stage. However, only a few constructs have been used in the clinic. The lack of standardization in evaluation methods employed may in part be responsible for this discrepancy. This review covers the most well-known and up-to-date methods for evaluating the optimization of new TESSs and orientative guidelines for the evaluation of TESSs are proposed.
%K biochemical methods
%K biomechanical evaluation
%K histological techniques
%K quality control
%K skin tissue engineering
%~