TY - JOUR AU - Espejo-Roman, Jose M AU - Rubio-Ruiz, Belen AU - Cano-Cortes, Victoria AU - Cruz-Lopez, Olga AU - Gonzalez-Resines, Saul AU - Domene, Carmen AU - Conejo-Garcia, Ana AU - Sanchez-Martin, Rosario M PY - 2022 DO - 10.3390/pharmaceutics14040788 SN - 1999-4923 UR - http://hdl.handle.net/10668/21548 T2 - Pharmaceutics AB - Hyaluronic acid (HA), through its interactions with the cluster of differentiation 44 (CD44), acts as a potent modulator of the tumor microenvironment, creating a wide range of extracellular stimuli for tumor growth, angiogenesis, invasion, and... LA - en PB - MDPI AG KW - anticancer therapy KW - cluster of differentiation 44 KW - hyaluronic acid KW - molecular dynamics simulations KW - nanomedicine KW - selective release KW - tetrahydroisoquinoline KW - Hyaluronic Acid KW - Cell Movement KW - Binding Sites KW - Neovascularization, Pathologic KW - Neoplastic Processes KW - Neoplasms KW - Tumor Microenvironment KW - Drug Liberation KW - Cell Survival TI - Selective Anticancer Therapy Based on a HA-CD44 Interaction Inhibitor Loaded on Polymeric Nanoparticles. TY - research article VL - 14 ER -