RT Generic
T1 Sepsis: A Review of Advances in Management
A1 Rello, Jordi
A1 Valenzuela-Sanchez, Francisco
A1 Ruiz-Rodriguez, Maria
A1 Moyano, Silvia
K1 Bacteremia
K1 Critically ill patients
K1 Pneumonia
K1 Sepsis
K1 Septic shock
K1 Critically-ill patients
K1 C-reactive protein
K1 Hla-dr expression
K1 Regional pro-adrenomedullin
K1 Goal-directed therapy
K1 Septic shock
K1 Immunomodulatory therapy
K1 Antimicrobial therapy
K1 Emergency-department
K1 Antibiotic-therapy
AB Infections represent a common health problem in people of all ages. Usually, the response given to them is appropriate and so little treatment is needed. Sometimes, however, the response to the infection is inadequate and may lead to organ dysfunction; this is the condition known as sepsis. Sepsis can be caused by bacteria, fungi or viruses and at present there is no specific treatment; its management basically focuses on containing the infection through source control and antibiotics plus organ function support. This article reviews key elements of sepsis management, focusing on diagnosis, biomarkers and therapy. The main recent advance in therapy is the strategy of personalized medicine, based on a precise approach using biomarkers to identify specific individuals who are likely to benefit from more personalized attention.
PB Springer
SN 0741-238X
YR 2017
FD 2017-11-01
LK https://hdl.handle.net/10668/25024
UL https://hdl.handle.net/10668/25024
LA en
DS RISalud
RD Apr 8, 2025