RT Journal Article
T1 Cross-sectional associations of objectively-measured sleep characteristics with obesity and type 2 diabetes in the PREDIMED-Plus trial.
A1 Rosique-Esteban, Nuria
A1 Papandreou, Christopher
A1 Romaguera, Dora
A1 Warnberg, Julia
A1 Corella, Dolores
A1 Martinez-Gonzalez, Miguel Angel
A1 Diaz-Lopez, Andres
A1 Estruch, Ramon
A1 Vioque, Jesus
A1 Aros, Fernando
A1 Garcia-Rios, Antonio
A1 Bueno-Cavanillas, Aurora
A1 Vidal, Josep
A1 Serra-Majem, Lluis
A1 Sibai, Abdurrahman Adlbi
A1 Tinahones, Francisco J
A1 Martinez, J Alfredo
A1 Ordovas, Jose M
A1 Tur, Josep A
A1 Ellacuria, Macarena Torrego
A1 Sanllorente, Albert
A1 Pinto, Xavier
A1 Buil-Cosiales, Pilar
A1 Fernandez-Carrion, Rebeca
A1 Castañer, Olga
A1 Bullo, Monica
A1 Ruiz-Canela, Miguel
A1 Garcia-de la Hera, Manoli
A1 Perez-Farinos, Napoleon
A1 Baron-Lopez, F Javier
A1 Colom, Antoni
A1 Abete, Itziar
A1 Ros, Emilio
A1 Salas-Salvado, Jordi
K1 Accelerometry
K1 Adiposity
K1 Aged
K1 Body mass index
AB To examine independent and combined associations of sleep duration and sleep variability with body composition, obesity and type 2 diabetes (T2D) in elders at high cardiovascular risk. Cross-sectional analysis of 1986 community-dwelling elders with overweight/obesity and metabolic syndrome from PREDIMED-Plus trial. Associations of accelerometry-derived sleep duration and sleep variability with body mass index (BMI), waist circumference (WC) and body composition were assessed fitting multivariable-adjusted linear regression models. Prevalence ratios (PR) and 95% confidence intervals (CI) for obesity and T2D were obtained using multivariable-adjusted Cox regression with constant time. "Bad sleepers" (age-specific non-recommended sleep duration plus sleep variability above the median) and "good sleepers" (age-specific recommended sleep duration plus sleep variability below the median) were characterized by combining sleep duration and sleep variability, and their associations with these outcomes were examined. One hour/night increment in sleep duration was inversely associated with BMI (β -0.38 kg/m2 [95% CI -0.54, -0.23]), WC (β -0.86 cm [95% CI -1.25, -0.47]), obesity (PR 0.96 [95% CI 0.93, 0.98]), T2D (PR 0.93 [95% CI 0.88, 0.98]) and other DXA-derived adiposity-related measurements (android fat and trunk fat, all p  This study revealed cross-sectional associations of sleep duration with adiposity parameters and obesity. Sleep duration and sleep variability were associated with T2D. Considering simultaneously sleep duration and sleep variability could have additional value, particularly for T2D, as they may act synergistically.
PB Oxford University Press
YR 2018
FD 2018
LK http://hdl.handle.net/10668/13027
UL http://hdl.handle.net/10668/13027
LA en
NO Rosique-Esteban N, Papandreou C, Romaguera D, Warnberg J, Corella D, Martínez-González MÁ, et al. Cross-sectional associations of objectively-measured sleep characteristics with obesity and type 2 diabetes in the PREDIMED-Plus trial. Sleep. 2018 Dec 1;41(12)
DS RISalud
RD Apr 18, 2025