RT Journal Article
T1 The immune boundaries for stem cell based therapies: problems and prospective solutions.
A1 Hmadcha, Abdelkrim
A1 Domínguez-Bendala, Juan
A1 Wakeman, Jane
A1 Mohamed, Arredouani
A1 Soria, Bernat
K1 Stem cells
K1 Histocompatibility
K1 Immune rejection
K1 Cell therapies
K1 Células Madre
K1 Histocompatibilidad
K1 Tratamiento Basado en Trasplante de Células y Tejidos
AB Stem cells have fascinated the scientific and clinical communities for over a century. Despite the controversy that surrounds this field, it is clear that stem cells have the potential to revolutionize medicine. However, a number of significant hurdles still stand in the way of the realization of this potential. Chiefly among these are safety concerns, differentiation efficiency and overcoming immune rejection. Here we review current progress made in this field to optimize the safe use of stem cells with particular emphasis on prospective interventions to deal with challenges generated by immune rejection.
PB Wiley
SN 1582-1838
YR 2009
FD 2009-08
LK http://hdl.handle.net/10668/2256
UL http://hdl.handle.net/10668/2256
LA en
NO Hmadcha A, Domínguez-Bendala J, Wakeman J, Mohamed, Soria B. The immune boundaries for stem cell based therapies: problems and prospective solutions. J. Cell. Mol. Med.. 2009; 13(8A):1464-75
NO Journal Article; Research Support, Non-U.S. Gov't; Review;
DS RISalud
RD Apr 9, 2025