RT Journal Article
T1 Role of NAFLD on the Health Related QoL Response to Lifestyle in Patients With Metabolic Syndrome: The PREDIMED Plus Cohort.
A1 Martinez-Urbistondo, Diego
A1 San Cristobal, RodrigoSan
A1 Villares, Paula
A1 Martinez-Gonzalez, Miguel Angel
A1 Babio, Nancy
A1 Corella, Dolores
A1 Del Val, Jose Luis
A1 Ordovas, Jose M
A1 Alonso-Gomez, Angel M
A1 Wärnberg, Julia
A1 Vioque, Jesus
A1 Romaguera, Dora
A1 Lopez-Miranda, Jose
A1 Estruch, Ramon
A1 Tinahones, Francisco J
A1 Lapetra, Jose
A1 Serra-Majem, J Luis
A1 Bueno-Cavanillas, Aurora
A1 Tur, Josep A
A1 Marcos, Alba
A1 Pinto, Xavier
A1 Delgado-Rodriguez, Miguel
A1 Matia-Martin, Pilar
A1 Vidal, Josep
A1 Vazquez, Clotilde
A1 Ros, Emilio
A1 Bullon Vela, Maria Vanessa
A1 Palau, Antoni
A1 Masague, Marta
A1 Abete, Itziar
A1 Moreno-Rodriguez, Anai
A1 Candela-Garcia, Inma
A1 Konieczna, Jadwiga
A1 Garcia-Rios, Antonio
A1 Juarez, Oscar Lecea
A1 Martin, Paco
A1 Goday, Albert
A1 Zulet, M Angeles
A1 Vaquero-Luna, Jessica
A1 Orea, Maria Del Carmen Sayon
A1 Megias, Isabel
A1 Baltasar, Enric
A1 Martinez, J Alfredo
A1 Daimiel, Lidia
K1 HRQoL
K1 NAFLD
K1 Mediterranean diet
K1 Metabolic syndrome
K1 Physical activity
AB To evaluate the effect of Non-alcoholic fatty liver disease (NAFLD) status in the impact of lifestyle over Health-related quality of life (HRQoL) in patients with metabolic syndrome (MetS). Baseline and 1 year follow up data from the PREDIMED-plus cohort (men and women, 55-75 years old with overweight/obesity and MetS) were studied. Adherence to an energy-restricted Mediterranean Diet (er-MeDiet) and Physical Activity (PA) were assessed with a validated screeners. Hepatic steatosis index (HSI) was implemented to evaluate NAFLD while the SF-36 questionnaire provided HRQoL evaluation. Statistical analyses were performed to evaluate the influence of baseline NAFLD on HRQoL as affected by lifestyle during 1 year of follow up. Data from 5205 patients with mean age of 65 years and a 48% of female participants. Adjusted linear multivariate mixed regression models showed that patients with lower probability of NAFLD (HSI  The evaluation of NAFLD by the HSI index in patients with MetS might identify subjects with different prospective sensitivity to lifestyle changes in terms of physical HRQoL 
PB Frontiers Research Foundation
SN 1664-2392
YR 2022
FD 2022-04-26
LK http://hdl.handle.net/10668/20564
UL http://hdl.handle.net/10668/20564
LA en
NO Martínez-Urbistondo D, San Cristóbal R, Villares P, Martínez-González MÁ, Babio N, Corella D, et al. Role of NAFLD on the Health Related QoL Response to Lifestyle in Patients With Metabolic Syndrome: The PREDIMED Plus Cohort. Front Endocrinol (Lausanne). 2022 Jun 29;13:868795
DS RISalud
RD Apr 8, 2025