%0 Journal Article
%A Ruiz-Moreno, Maria Isabel
%A Vilches-Perez, Alberto
%A Gallardo-Escribano, Cristina
%A Vargas-Candela, Antonio
%A Lopez-Carmona, Maria Dolores
%A Pérez-Belmonte, Luis Miguel
%A Ruiz-Moreno, Alejandro
%A Gómez-Huelgas, Ricardo
%A Bernal-Lopez, Maria Rosa
%T Metabolically Healthy Obesity: Presence of Arterial Stiffness in the Prepubescent Population
%D 2020
%@ 1661-7827
%U http://hdl.handle.net/10668/4377
%X Aim: Arteriosclerotic cardiovascular disease, one of the world’s leading causes of death, first manifests itself at an early age. The identification of children who may have increased cardiovascular risk in the future could be an important prevention strategy. Our aim was to assess the clinical, analytical, and dietary variables associated with arterial stiffness (AS), measured by carotid-femoral pulse wave velocity (cfPWV) in a prepubescent population with metabolically healthy obesity (MHO). Subjects and Methods: A cross-sectional study in prepubescent subjects with obesity who had ≤1 metabolic syndrome criteria (abdominal perimeter and blood pressure ≥90th percentile, triglycerides >150 mg/dL, HDL-cholesterol < 0.0001), BMI (r = 0.44; p < 0.0001), WHtR (r = 0.26; p = 0.02), fasting insulin levels (r = 0.28; p = 0.02), and insulin resistance (Homeostatic Model Assessment of Insulin Resistance (HOMA-IR) index) (r = 0.25; p = 0.04). Multiple linear regression analysis identified BMI and HOMA-IR as independent parameters associated with cfPWV. Conclusions: Prepubescent children with obesity who were shown to be metabolically healthy presented with arterial stiffness, which is closely related to BMI and the state of insulin resistance.
%K Arterial stiffness
%K Carotid-femoral pulse wave velocity
%K Prepubescent population
%K Mediterranean diet
%K Insulin resistance
%K Metabolically healthy obesity
%K Rigidez vascular
%K Velocidad de la onda del pulso carotídeo-femoral
%K Dieta mediterránea
%K Resistencia a la insulina
%K Obesidad metabólica benigna
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