TY  - JOUR
AU  - Hernandez-Munoz, Inmaculada
AU  - Figuerola, Elisabeth
AU  - Sanchez-Molina, Sara
AU  - Rodriguez, Eva
AU  - Isabel Fernandez-Marino, Ana
AU  - Pardo-Pastor, Carlos
AU  - Isabel Bahamonde, Maria
AU  - Fernandez-Fernandez, Jose M.
AU  - Garcia-Dominguez, Daniel J.
AU  - Hontecillas-Prieto, Lourdes
AU  - Lavarino, Cinzia
AU  - Carcaboso, Angel M.
AU  - de Torres, Carmen
AU  - Tirado, Oscar M.
AU  - de Alava, Enrique
AU  - Mora, Jaume
PY  - 2016
DO  - 10.18632/oncotarget.10092
UR  - http://hdl.handle.net/10668/19432
T2  - Oncotarget
AB  - Ewing sarcoma (ES) is an aggressive tumor defined by EWSR1 gene fusions that behave as an oncogene. Here we demonstrate that RING1B is highly expressed in primary ES tumors, and its expression is independent of the fusion oncogene. RING1B-depleted ES...
LA  - en
PB  - Impact journals llc
KW  - RING1B
KW  - Ewing sarcoma
KW  - voltage-gated sodium channel
KW  - NF-kappa B
KW  - FGFR/SHP2/STAT3
KW  - Fibroblast-growth-factor
KW  - Marrow stromal cells
KW  - In-vivo
KW  - Neuroectodermal tumors
KW  - Neural differentiation
KW  - Tyrosine-phosphatase
KW  - Genomic landscape
KW  - Histone h2a
KW  - Stem-cells
KW  - Family
TI  - RING1B contributes to Ewing sarcoma development by repressing the Na(V)1.6 sodium channel and the NF-kappa B pathway, independently of the fusion oncoprotein
TY  - research article
VL  - 7
ER  -