RT Journal Article T1 Associations Between the Modified Food Standard Agency Nutrient Profiling System Dietary Index and Cardiovascular Risk Factors in an Elderly Population. A1 Khoury, Nadine A1 Gomez-Donoso, Clara A1 Martinez, Maria Angeles A1 Martinez-Gonzalez, Miguel Angel A1 Corella, Dolores A1 Fito, Montserrat A1 Martinez, J Alfredo A1 Alonso-Gomez, Angel M A1 Wärnberg, Julia A1 Vioque, Jesus A1 Romaguera, Dora A1 Leon-Acuña, Ana A1 Tinahones, Francisco J A1 Santos-Lozano, Jose M A1 Serra-Majem, Luis A1 Masso Guijarro, Paloma A1 Tur, Josep A A1 Martin Sanchez, Vicente A1 Pinto, Xavier A1 Delgado-Rodriguez, Miguel A1 Matia-Martin, Pilar A1 Vidal, Josep A1 Vazquez, Clotilde A1 Daimiel, Lidia A1 Ros, Emili A1 Bes-Rastrollo, Maira A1 Barragan, Rocio A1 Castañer, Olga A1 Torres-Peña, Jose D A1 Notario-Barandiaran, Leyre A1 Muñoz-Bravo, Carlos A1 Abete, Itziar A1 Prohens, Lara A1 Cano-Ibañez, Naomi A1 Tojal Sierra, Lucas A1 Fernandez-Garcia, Jose Carlos A1 Sayon-Orea, Carmen A1 Pascual, Maria A1 Sorli, Jose V A1 Zomeño, Dolores A1 Peña-Orihuela, Patricia J A1 Signes-Pastor, Antonio J A1 Basterra-Gortari, F Javier A1 Schröeder, Helmut A1 Salas Salvado, Jordi A1 Babio, Nancy K1 FSAm-NPS dietary index K1 PREDIMED-Plus study K1 Body weight K1 Cardiovascular risk factor K1 Front of pack food labeling AB Helping consumers to improve the nutritional quality of their diet is a key public health action to prevent cardiovascular diseases (CVDs). The modified version of the Food Standard Agency Nutrient Profiling System Dietary Index (FSAm-NPS DI) underpinning the Nutri-Score front-of-pack label has been used in public health strategies to address the deleterious consequences of poor diets. This study aimed to assess the association between the FSAm-NPS DI and some CVD risk factors including body mass index (BMI), waist circumference, plasma glucose levels, triglyceride levels, high-density lipoprotein (HDL) and low-density lipoprotein (LDL) cholesterol, and diastolic and systolic blood pressure. Dietary intake was assessed at baseline and after 1 year of follow-up using a 143-item validated semi-quantitative food-frequency questionnaire. Dietary indices based on FSAm-NPS applied at an individual level were computed to characterize the diet quality of 5,921 participants aged 55-75 years with overweight/obesity and metabolic syndrome from the PREDIMED-plus cohort. Associations between the FSAm-NPS DI and CVD risk factors were assessed using linear regression models. Compared to participants with a higher nutritional quality of diet (measured by a lower FSAm-NPS DI at baseline or a decrease in FSAm-NPS DI after 1 year), those participants with a lower nutritional quality of diet (higher FSAm-NPS DI or an increase in score) showed a significant increase in the levels of plasma glucose, triglycerides, diastolic blood pressure, BMI, and waist circumference (β coefficient [95% confidence interval]; P for trend) (1.67 [0.43, 2.90]; This prospective cohort study suggests that the consumption of food items with a higher FSAm-NPS DI is associated with increased levels of several major risk factors for CVD including adiposity, fasting plasma glucose, triglycerides, and diastolic blood pressure. However, results must be cautiously interpreted because no significant prospective associations were identified for critical CVD risk factors, such as HDL and LDL-cholesterol, and systolic blood pressure. PB Frontiers Research Foundation SN 2296-861X YR 2022 FD 2022-06-22 LK http://hdl.handle.net/10668/20666 UL http://hdl.handle.net/10668/20666 LA en NO Khoury N, Gómez-Donoso C, Martínez MÁ, Martínez-González MÁ, Corella D, Fitó M, et al. Associations Between the Modified Food Standard Agency Nutrient Profiling System Dietary Index and Cardiovascular Risk Factors in an Elderly Population. Front Nutr. 2022 Jul 14;9:897089 DS RISalud RD Apr 15, 2025