TY - JOUR AU - Vitallé, Joana AU - Terrén, Iñigo AU - Gamboa-Urquijo, Leire AU - Orrantia, Ane AU - Tarancón-Díez, Laura AU - Genebat, Miguel AU - Leal, Manuel AU - Ruiz-Mateos, Ezequiel AU - Borrego, Francisco AU - Zenarruzabeitia, Olatz PY - 2020 DO - 10.1038/s41598-020-63025-4 UR - http://hdl.handle.net/10668/4112 T2 - Scientific Reports AB - CD300a receptor is found on different CD8+ T cell subsets and its expression has been associated to a more cytotoxic molecular signature. CD300a has an important role in some viral infections and its expression levels are known to be modulated by... LA - en PB - Springer Nature KW - HIV-1 KW - Cytokines KW - Peptides KW - CD300a receptor KW - T-Lymphocytes KW - Citocinas KW - Péptidos KW - Linfocitos T KW - Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Therapeutic Uses::Anti-Infective Agents::Antiviral Agents::Anti-Retroviral Agents::Anti-HIV Agents KW - Medical Subject Headings::Chemicals and Drugs::Biological Factors::Antigens::Antigens, Surface::Antigens, Differentiation::Antigens, CD KW - Medical Subject Headings::Anatomy::Cells::Blood Cells::Leukocytes::Leukocytes, Mononuclear::Lymphocytes::T-Lymphocytes::CD8-Positive T-Lymphocytes KW - Medical Subject Headings::Anatomy::Cells::Cells, Cultured KW - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Intercellular Signaling Peptides and Proteins::Cytokines KW - Medical Subject Headings::Diseases::Immune System Diseases::Immunologic Deficiency Syndromes::HIV Infections KW - Medical Subject Headings::Organisms::Viruses::RNA Viruses::Retroviridae::Lentivirus::Lentiviruses, Primate::HIV::HIV-1 KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans KW - Medical Subject Headings::Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::Biochemical Processes::Up-Regulation KW - Medical Subject Headings::Anatomy::Cells::Blood Cells::Leukocytes::Leukocytes, Mononuclear::Lymphocytes::T-Lymphocytes::T-Lymphocyte Subsets KW - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Peptides TI - Polyfunctional HIV-1 specific response by CD8+ T lymphocytes expressing high levels of CD300a TY - research article ER -