RT Journal Article
T1 Hemophagocytic syndrome, a diagnostic challenge in Gastroenterology.
A1 Jiménez Rosales, Rita
A1 Martín-Rodríguez, María Del Mar
A1 Redondo-Cerezo, Eduardo
AB Hemophagocytic lymphohistiocytosis is a syndrome of severe immune activation with macrophage and T- cell infiltration resulting in multi organ damage. We report the case of a patient successfully treated for a haemophagocytic syndrome triggered by a metastatic neoplasm of the rectum. A 57 years old man is initially presented with fever without focus. Despite of wide spectrum antibiotics he developed a multi-organ dysfunction. A bone marrow aspirate showed histiocytes that had phagocytosed hematic cells. Hemophagocytic syndrome was suspected and specific treatment was administered. The patient's condition improved remarkably and he was discharged. Nevertheles, finally, the patient died due to a bad response to chemotherapy. Malignancies are a well known triggering of hemophagocytic lymphohistiocytosis being hematological the most commun malignancy associated. However, solid tumors are anecdotic and, to our knowledge, this case is the first one documented due only to rectal carcinoma.
SN 1130-0108
YR 2019
FD 2019
LK http://hdl.handle.net/10668/14530
UL http://hdl.handle.net/10668/14530
LA en
DS RISalud
RD Apr 4, 2025