RT Journal Article T1 Synthetic biology approaches to actinomycete strain improvement. A1 Breitling, Rainer A1 Avbelj, Martina A1 Bilyk, Oksana A1 Carratore, Francesco Del A1 Filisetti, Alessandro A1 Hanko, Erik K R A1 Iorio, Marianna A1 Redondo, Rosario Pérez A1 Reyes, Fernando A1 Rudden, Michelle A1 Severi, Emmanuele A1 Slemc, Lucija A1 Schmidt, Kamila A1 Whittall, Dominic R A1 Donadio, Stefano A1 García, Antonio Rodríguez A1 Genilloud, Olga A1 Kosec, Gregor A1 De Lucrezia, Davide A1 Petković, Hrvoje A1 Thomas, Gavin A1 Takano, Eriko K1 actinobacteria K1 actinomycete K1 biosynthesis K1 biotechnology K1 synthetic biology AB Their biochemical versatility and biotechnological importance make actinomycete bacteria attractive targets for ambitious genetic engineering using the toolkit of synthetic biology. But their complex biology also poses unique challenges. This mini review discusses some of the recent advances in synthetic biology approaches from an actinomycete perspective and presents examples of their application to the rational improvement of industrially relevant strains. YR 2021 FD 2021 LK http://hdl.handle.net/10668/17855 UL http://hdl.handle.net/10668/17855 LA en DS RISalud RD Apr 8, 2025