TY - JOUR AU - Elena-Real, Carlos A AU - Díaz-Quintana, Antonio AU - González-Arzola, Katiuska AU - Velázquez-Campoy, Adrián AU - Orzáez, Mar AU - López-Rivas, Abelardo AU - Gil-Caballero, Sergio AU - De la Rosa, Miguel Á AU - Díaz-Moreno, Irene PY - 2018 DO - 10.1038/s41419-018-0408-1 UR - http://hdl.handle.net/10668/12211 T2 - Cell death & disease AB - Apoptosis is a highly regulated form of programmed cell death, essential to the development and homeostasis of multicellular organisms. Cytochrome c is a central figure in the activation of the apoptotic intrinsic pathway, thereby activating the... LA - en KW - 14-3-3 Proteins KW - Amino Acid Motifs KW - Apoptotic Protease-Activating Factor 1 KW - Caspase 3 KW - Caspase 9 KW - Cytochromes c KW - Cytosol KW - Enzyme Activation KW - Humans KW - Protein Binding TI - Cytochrome c speeds up caspase cascade activation by blocking 14-3-3ε-dependent Apaf-1 inhibition. TY - research article VL - 9 ER -