RT Journal Article T1 Chronic Fatigue, Physical Impairments and Quality of Life in Women with Endometriosis: A Case-Control Study A1 Álvarez-Salvago, Francisco A1 Lara-Ramos, Ana A1 Cantarero-Villanueva, Irene A1 Mazheika, Maryna A1 Mundo-López, Antonio A1 Galiano-Castillo, Noelia A1 Fernández-Lao, Carolina A1 Arroyo-Morales, Manuel A1 Ocón-Hernández, Olga A1 Artacho-Cordón, Francisco K1 Chronic fatigue K1 Endometriosis K1 Health-related fitness K1 Health-related quality of life K1 Sleep quality K1 Síndrome de fatiga crónica K1 Calidad de vida K1 Calidad del sueño AB Abstract: Aim: To explore endometriosis-related fatigue (ERF), health-related fitness, sleep quality, and health-related quality of life (HRQoL) in women with endometriosis in comparison with matched controls. Methods: Twenty-five affected women and twenty-five age and height-matched women without endometriosis were included. ERF was assessed through the Piper Fatigue Scale; health-related fitness was assessed through the Schöber, flamingo, and 6-min walking tests and dynamometry; and body composition was assessed through impedanciometry. Self-perceived physical fitness, sleep quality, and HRQoL were assessed through the International Fitness Scale, the Pittsburgh Sleep Quality Index, and the 12-item Short Form Health Survey, respectively. Results: Affected women exhibited higher levels of ERF than controls, increased fat mass, and physical deconditioning (reduced back strength, lumbar flexibility, body balance, and functional capacity, p-values < 0.050). Moreover, cases also had poorer perceived physical fitness, sleep quality, and HRQoL (p-value < 0.050). Finally, we observed deteriorated health-related fitness, sleep quality, and HRQoL in those women with endometriosis with higher levels of ERF. Conclusions: This study constitutes the first evidence that women with endometriosis describe a generalized physical deconditioning, even more pronounced in affected women with higher levels of ERF. Further studies assessing the efficacy of rehabilitation interventions to face these physical impairments in women with endometriosis are warranted. PB MDPI YR 2020 FD 2020-05-21 LK http://hdl.handle.net/10668/3910 UL http://hdl.handle.net/10668/3910 LA en NO Álvarez-Salvago F, Lara-Ramos A, Cantarero-Villanueva I, Mazheika M, Mundo-López A, Galiano-Castillo N, et al. Chronic Fatigue, Physical Impairments and Quality of Life in Women with Endometriosis: A Case-Control Study. Int J Environ Res Public Health. 2020 May 21;17(10):3610 DS RISalud RD Apr 4, 2025