TY - JOUR AU - Ocana, Alberto AU - Gil-Martin, Marta AU - Martín, Miguel AU - Rojo, Federico AU - Antolín, Silvia AU - Guerrero, Ángel AU - Trigo, José Manuel AU - Muñoz, Montse AU - Pandiella, Atanasio AU - Diego, Núria Gonzalo AU - Bezares, Susana AU - Caballero, Rosalía AU - Carrasco, Eva AU - Urruticoechea, Ander PY - 2017 DO - 10.18632/oncotarget.17113 UR - https://hdl.handle.net/10668/25132 T2 - Oncotarget AB - The anti-HER2 antibody trastuzumab have shown clinical activity in combination with chemotherapy in different breast cancer settings. However, most of patients treated with this antibody progress after a period of treatment. Activation of the kinase... LA - en KW - HER2 positive breast cancer KW - SRC kinase KW - dasatinib KW - metastatic breast cancer KW - trastuzumab resistance TI - A phase I study of the SRC kinase inhibitor dasatinib with trastuzumab and paclitaxel as first line therapy for patients with HER2-overexpressing advanced breast cancer. GEICAM/2010-04 study. TY - research article VL - 8 ER -