RT Journal Article
T1 Obstetric and Perinatal Outcomes after Very Early Preterm Premature Rupture of Membranes (PPROM)-A Retrospective Analysis over the Period 2000-2020
A1 González-Mesa, Ernesto
A1 Blasco-Alonso, Marta
A1 Benítez, María José
A1 Gómez-Muñoz, Cristina
A1 Sabonet-Morente, Lorena
A1 Gómez-Castellanos, Manuel
A1 Ulloa, Osmayda
A1 González-Cazorla, Ernesto
A1 Puertas-Prieto, Alberto
A1 Mozas-Moreno, Juan
A1 Jiménez-López, Jesús
A1 Lubián-López, Daniel
K1 Very early PPROM
K1 Premature rupture of fetal membranes
K1 Perinatal mortality
K1 Premature birth
K1 Gestational age
K1 Pregnancy
K1 Rotura prematura de membranas fetales
K1 Mortalidad perinatal
K1 Nacimiento prematuro
K1 Edad gestacional
K1 Embarazo
AB Background and Objectives: Pre-term premature rupture of membranes (PPROM) responds for one third of preterm births, and it is associated with other complications that increase the risk of maternal or fetal poor outcome. To reduce uncertainty and provide accurate information to patients, the analysis of the large series is of great importance. In order to learn about the evolution over the time of the obstetric and perinatal outcomes in cases of PPROM at, or before, 28 weeks (very early PPROM) managed with an expectant/conservative protocol, we have designed the present study. Materials and Methods: We retrospectively studied all cases of very early PPROM attended in Malaga University Regional Hospital from 2000 to 2020. Results: Among 119,888 deliveries assisted, 592 cases of PPROM occurred in pregnancies at or before 28 weeks (0.49% of all deliveries, 3.9% of all preterm births and 12.9% of all cases of PPROM). The mean duration of the latency period between PPROM and delivery was 13.5 days (range 0 to 88 days), enlarging over the years. The mean gestational age at delivery was 27 weeks (SD 2.9; range 17-34). The proportion of cesarean deliveries was 52.5%. The overall perinatal mortality rate was 26.5%, decreasing over the period with a significant correlation Pearson's coefficient -0.128 (p < 0.05). Conclusions: In the period 2000-2020, there was an improvement in the outcomes of very early PPROM cases and perinatal mortality showed a clear trend to decrease.
PB MDPI
SN 1010-660X
YR 2021
FD 2021-05-11
LK http://hdl.handle.net/10668/4073
UL http://hdl.handle.net/10668/4073
LA en
NO González-Mesa E, Blasco-Alonso M, Benítez MJ, Gómez-Muñoz C, Sabonet-Morente L, Gómez-Castellanos M, et al. Obstetric and Perinatal Outcomes after Very Early Preterm Premature Rupture of Membranes (PPROM)-A Retrospective Analysis over the Period 2000-2020. Medicina. 2021 May 11;57(5):469.
DS RISalud
RD Apr 6, 2025