TY  - JOUR
AU  - González, Raúl
AU  - Rodríguez-Hernández, María A.
AU  - Negrete, María
AU  - Ranguelova, Kalina
AU  - Rossin, Aurelie
AU  - Choya-Foces, Carmen
AU  - de la Cruz-Ojeda, Patricia
AU  - Miranda-Vizuete, Antonio
AU  - Martínez-Ruiz, Antonio
AU  - Rius-Pérez, Sergio
AU  - Sastre, Juan
AU  - Bárcena, José A.
AU  - Hueber, Anne-Odile
AU  - Padilla, C. Alicia
AU  - Muntané, Jordi
PY  - 2020
DO  - 10.1016/j.redox.2020.101528
UR  - http://hdl.handle.net/10668/4548
T2  - Redox Biology
AB  - Hepatocellular carcinoma (HCC) represents 80% of the primary hepatic neoplasms. It is the sixth most frequent neoplasm, the fourth cause of cancer-related death, and 7% of registered malignancies. Sorafenib is the first line molecular targeted therapy...
LA  - en
PB  - Elsevier
KW  - Apoptosis
KW  - Cell proliferation
KW  - CD95
KW  - GSNOR
KW  - Hepatocarcinoma
KW  - Nrf2
KW  - NOS3
KW  - Thioredoxins
KW  - Liver cancer
KW  - Downregulation
KW  - Proliferación celular
KW  - S-Nitrosoglutatión
KW  - Carcinoma hepatocelular
KW  - Factor 2 relacionado con NF-E2
KW  - Óxido nítrico sintasa de tipo III
KW  - Tiorredoxinas
KW  - Neoplasias hepáticas
KW  - Regulación hacia abajo
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals
KW  - Medical Subject Headings::Anatomy::Cells::Cells, Cultured::Cell Line::Cell Line, Tumor
KW  - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Growth Processes::Cell Proliferation
KW  - Medical Subject Headings::Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::Biochemical Processes::Down-Regulation
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Mice
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Mice::Mice, Mutant Strains::Mice, Nude
KW  - Medical Subject Headings::Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::Biochemical Processes::Nitrosation
KW  - Medical Subject Headings::Chemicals and Drugs::Organic Chemicals::Hydrocarbons::Hydrocarbons, Cyclic::Hydrocarbons, Aromatic::Benzene Derivatives::Phenylurea Compounds
KW  - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Thioredoxins
KW  - Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Therapeutic Uses::Antineoplastic Agents
KW  - Medical Subject Headings::Diseases::Neoplasms::Neoplasms by Site::Digestive System Neoplasms::Liver Neoplasms::Carcinoma, Hepatocellular
KW  - Medical Subject Headings::Diseases::Neoplasms::Neoplasms by Site::Digestive System Neoplasms::Liver Neoplasms
TI  - Downregulation of thioredoxin-1-dependent CD95 S-nitrosation by Sorafenib reduces liver cancer
TY  - research article
ER  -