TY - JOUR AU - Ríos-Arrabal, Sandra AU - Puentes-Pardo, Jose D. AU - Moreno-SanJuan, Sara AU - Szuba, Ágata AU - Casado, Jorge AU - García-Costela, María AU - Escudero-Feliu, Julia AU - Verbeni, Michela AU - Cano, Carlos AU - González-Puga, Cristina AU - Martín-Lagos Maldonado, Alicia AU - Carazo, Ángel AU - León, Josefa PY - 2021 DO - 10.3390/jpm11060509 UR - http://hdl.handle.net/10668/3524 T2 - Journal of Personalized Medicine AB - Heme oxygenase-1 (HO-1) is an antioxidant protein implicated in tumor progression, metastasis, and resistance to therapy. Elevated HO-1 expression is associated with stemness in several types of cancer, although this aspect has not yet been studied in... LA - en PB - MDPI KW - Colorectal cancer KW - Cancer stem cells KW - Heme oxygenase-1 KW - Endothelin-1 KW - Endothelin converting enzyme-1 KW - Bosentan KW - Neoplasias colorrectales KW - Hemo-oxigenasa 1 KW - Endotelina-1 KW - Bosentán KW - Medical Subject Headings::Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Oxidoreductases::Oxygenases::Mixed Function Oxygenases::Heme Oxygenase (Decyclizing)::Heme Oxygenase-1 KW - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins KW - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Peptides::Intercellular Signaling Peptides and Proteins::Endothelins::Endothelin-1 KW - Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Specialty Uses of Chemicals::Protective Agents::Antioxidants KW - Medical Subject Headings::Diseases::Neoplasms::Neoplasms by Site::Digestive System Neoplasms::Gastrointestinal Neoplasms::Intestinal Neoplasms::Colorectal Neoplasms TI - Endothelin-1 as a Mediator of Heme Oxygenase-1-Induced Stemness in Colorectal Cancer: Influence of p53 TY - research article ER -