TY - JOUR AU - Gabriel, Rafael AU - Boukichou Abdelkader, Nisa AU - Acosta, Tania AU - Gilis-Januszewska, Aleksandra AU - Gómez-Huelgas, Ricardo AU - Makrilakis, Konstantinos AU - Kamenov, Zdravko AU - Paulweber, Bernhard AU - Satman, Ilhan AU - Djordjevic, Predrag AU - Alkandari, Abdullah AU - Mitrakou, Asimina AU - Lalic, Nebojsa AU - Colagiuri, Stephen AU - Lindström, Jaana AU - Egido, Jesús AU - Natali, Andrea AU - Pastor, J Carlos AU - Teuschl, Yvonne AU - Lind, Marcus AU - Silva, Luis AU - López-Ridaura, Ruy AU - Tuomilehto, Jaakko AU - e-PREDICE Consortium PY - 2020 DO - 10.1371/journal.pone.0231196 UR - http://hdl.handle.net/10668/15362 T2 - PloS one AB - To assess the effects of early management of hyperglycaemia with antidiabetic drugs plus lifestyle intervention compared with lifestyle alone, on microvascular function in adults with pre-diabetes. Trial design: International, multicenter, randomised,... LA - en KW - Aged KW - Diabetes Complications KW - Diabetes Mellitus, Type 2 KW - Diabetic Nephropathies KW - Diabetic Neuropathies KW - Diabetic Retinopathy KW - Double-Blind Method KW - Europe KW - Female KW - Galvanic Skin Response KW - Humans KW - Hyperglycemia KW - International Cooperation KW - Life Style KW - Linagliptin KW - Male KW - Metformin KW - Microcirculation KW - Middle Aged KW - Patient Selection KW - Research Design KW - Risk Factors TI - Early prevention of diabetes microvascular complications in people with hyperglycaemia in Europe. ePREDICE randomized trial. Study protocol, recruitment and selected baseline data. TY - research article VL - 15 ER -