TY - JOUR AU - López de Andrés, Julia AU - Griñán-Lisón, Carmen AU - Jiménez, Gema AU - Marchal, Juan Antonio PY - 2020 DO - 10.1186/s13045-020-00966-3 UR - http://hdl.handle.net/10668/3605 T2 - Journal of Hematology & Oncology AB - Cancer stem cells (CSCs) represent a tumor subpopulation responsible for tumor metastasis and resistance to chemo- and radiotherapy, ultimately leading to tumor relapse. As a consequence, the detection and eradication of this cell subpopulation... LA - en PB - Springer Nature KW - Cancer stem cells KW - Tumor microenvironment KW - Secretome KW - Growth factors KW - Interleukins KW - miRNAs KW - Exosomes KW - Células madre neoplásicas KW - Microambiente tumoral KW - Factores de crecimiento endotelial vascular KW - Interleucinas KW - MicroARNs KW - Péptidos y proteínas de señalización intercelular KW - Medical Subject Headings::Organisms::Eukaryota::Animals KW - Medical Subject Headings::Anatomy::Cells::Cellular Structures::Intracellular Space::Cytoplasm::Cytoplasmic Structures::Organelles::Cytoplasmic Vesicles::Transport Vesicles::Exosomes KW - Medical Subject Headings::Anatomy::Cells::Cellular Structures::Extracellular Space::Extracellular Matrix KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans KW - Medical Subject Headings::Chemicals and Drugs::Biological Factors::Intercellular Signaling Peptides and Proteins KW - Medical Subject Headings::Chemicals and Drugs::Biological Factors::Intercellular Signaling Peptides and Proteins::Cytokines::Interleukins KW - Medical Subject Headings::Chemicals and Drugs::Nucleic Acids, Nucleotides, and Nucleosides::Nucleic Acids::RNA::RNA, Antisense::MicroRNAs KW - Medical Subject Headings::Diseases::Neoplasms KW - Medical Subject Headings::Anatomy::Cells::Stem Cells::Neoplastic Stem Cells KW - Medical Subject Headings::Diseases::Pathological Conditions, Signs and Symptoms::Pathologic Processes::Metaplasia::Neovascularization, Pathologic KW - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cellular Microenvironment::Tumor Microenvironment TI - Cancer stem cell secretome in the tumor microenvironment: a key point for an effective personalized cancer treatment TY - review article ER -