TY  - JOUR
AU  - Blanco, Ignacio
AU  - Bueno, Patricia
AU  - Diego, Isidro
AU  - Pérez-Holanda, Sergio
AU  - Casas-Maldonado, Francisco
AU  - Esquinas, Cristina
AU  - Miravitlles, Marc
PY  - 2017
DO  - 10.2147/COPD.S125389
SN  - 1176-9106
UR  - http://hdl.handle.net/10668/2622
T2  - International Journal of Chronic Obstructive Pulmonary Disease
AB  - In alpha-1 antitrypsin deficiency (AATD), the Z allele is present in 98% of cases with severe disease, and knowledge of the frequency of this allele is essential from a public health perspective. However, there is a remarkable lack of epidemiological...
LA  - en
PB  - Dove Medical Press
KW  - SERPINA1
KW  - Alpha-1 antitrypsin deficiency
KW  - Genetic epidemiology
KW  - Geographic information system
KW  - Inverse distance weighted interpolation
KW  - Protease inhibitor
KW  - África
KW  - Alelos
KW  - Región del Caribe
KW  - Intervalos de confianza
KW  - Europa (Continente)
KW  - Genotipo
KW  - Nueva Zelanda
KW  - Prevalencia
KW  - Salud Pública
KW  - Reproducibilidad de resultados
KW  - Tamaño de la Muestra
KW  - Deficiencia de alfa 1-antitripsina
KW  - Medical Subject Headings::Geographical Locations::Geographic Locations::Africa
KW  - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Structures::Genome::Genome Components::Genes::Alleles
KW  - Medical Subject Headings::Geographical Locations::Geographic Locations::Asia
KW  - Medical Subject Headings::Geographical Locations::Geographic Locations::Australia
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Confidence Intervals
KW  - Medical Subject Headings::Geographical Locations::Geographic Locations::Europe
KW  - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genotype
KW  - Medical Subject Headings::Geographical Locations::Geographic Locations::Islands::Pacific Islands::New Zealand
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Data Collection::Vital Statistics::Morbidity::Prevalence
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Research Design::Reproducibility of Results
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Research Design::Sample Size
KW  - Medical Subject Headings::Diseases::Congenital, Hereditary, and Neonatal Diseases and Abnormalities::Genetic Diseases, Inborn::alpha 1-Antitrypsin Deficiency
KW  - Medical Subject Headings::Geographical Locations::Geographic Locations::Americas::Caribbean Region
KW  - Medical Subject Headings::Health Care::Environment and Public Health::Public Health
TI  - Alpha-1 antitrypsin Pi*Z gene frequency and Pi*ZZ genotype numbers worldwide: an update.
TY  - research article
ER  -