TY  - JOUR
AU  - Qureshi, Rehana
AU  - Picon-Ruiz, Manuel
AU  - Aurrekoetxea-Rodriguez, Iskander
AU  - Nunes de Paiva, Vanessa
AU  - D'Amico, Massimo
AU  - Yoon, Hyunho
AU  - Radhakrishnan, Ramya
AU  - Morata-Tarifa, Cynthia
AU  - Ince, Tan
AU  - Lippman, Marc E
AU  - Thaller, Seth R
AU  - Rodgers, Steven E
AU  - Kesmodel, Susan
AU  - Vivanco, Maria Del Mar
AU  - Slingerland, Joyce M
PY  - 2020
DO  - 10.1016/j.cmet.2020.05.008
UR  - http://hdl.handle.net/10668/15673
T2  - Cell metabolism
AB  - Many inflammation-associated diseases, including cancers, increase in women after menopause and with obesity. In contrast to anti-inflammatory actions of 17β-estradiol, we find estrone, which dominates after menopause, is pro-inflammatory. In human...
LA  - en
PB  - Cell Press
KW  - 17β-estradiol
KW  - ER+ breast cancer
KW  - HSD17B14
KW  - NFκB
KW  - adipocytes
KW  - cancer stem cells
KW  - cytokines
KW  - estrone
KW  - inflammation
KW  - obesity
KW  - Animals
KW  - Breast Neoplasms
KW  - Cells, Cultured
KW  - Estrogens
KW  - Female
KW  - Humans
KW  - Inflammation
KW  - Mice
KW  - Mice, Congenic
KW  - Mice, Inbred C57BL
KW  - Mice, Transgenic
KW  - Obesity
KW  - Postmenopause
KW  - Premenopause
TI  - The Major Pre- and Postmenopausal Estrogens Play Opposing Roles in Obesity-Driven Mammary Inflammation and Breast Cancer Development.
TY  - research article
VL  - 31
ER  -