TY  - JOUR
AU  - Calvo-Rodriguez, Maria
AU  - Hou, Steven S.
AU  - Snyder, Austin C.
AU  - Kharitonova, Elizabeth K.
AU  - Russ, Alyssa N.
AU  - Das, Sudeshna
AU  - Fan, Zhanyun
AU  - Muzikansky, Alona
AU  - Garcia-Alloza, Monica
AU  - Serrano-Pozo, Alberto
AU  - Hudry, Eloise
AU  - Bacskai, Brian J.
PY  - 2020
DO  - 10.1038/s41467-020-16074-2
UR  - http://hdl.handle.net/10668/3567
T2  - Nature Communications
AB  - Mitochondria contribute to shape intraneuronal Ca2+ signals. Excessive Ca2+ taken up by mitochondria could lead to cell death. Amyloid beta (Aβ) causes cytosolic Ca2+ overload, but the effects of Aβ on mitochondrial Ca2+ levels in Alzheimer's disease...
LA  - en
PB  - Springer Nature
KW  - Mitochondria
KW  - Calcium
KW  - Cell death
KW  - Amyloid
KW  - Brain
KW  - Genes
KW  - Microscopy
KW  - Alzheimer disease
KW  - Lead
KW  - Mitocondrias
KW  - Calcio
KW  - Muerte celular
KW  - Amiloide
KW  - Encéfalo
KW  - Microscopía
KW  - Enfermedad de Alzheimer
KW  - Plomo
KW  - Medical Subject Headings::Diseases::Nervous System Diseases::Neurodegenerative Diseases::Tauopathies::Alzheimer Disease
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Genetic Techniques::Molecular Probe Techniques::Blotting, Western
KW  - Medical Subject Headings::Anatomy::Nervous System::Central Nervous System::Brain
KW  - Medical Subject Headings::Chemicals and Drugs::Inorganic Chemicals::Elements::Metals, Alkaline Earth::Calcium
KW  - Medical Subject Headings::Anatomy::Cells::Cells, Cultured
KW  - Medical Subject Headings::Anatomy::Cells::Cellular Structures::Intracellular Space::Cytoplasm::Cytosol
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Immunologic Techniques::Immunohistochemistry
KW  - Medical Subject Headings::Check Tags::Male
KW  - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Membrane Potentials::Membrane Potential, Mitochondrial
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Mice
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Animal Population Groups::Animals, Laboratory::Animals, Inbred Strains::Mice, Inbred Strains::Mice, Inbred C57BL
KW  - Medical Subject Headings::Anatomy::Cells::Cellular Structures::Intracellular Space::Cytoplasm::Cytoplasmic Structures::Organelles::Mitochondria
KW  - Medical Subject Headings::Diseases::Nervous System Diseases::Neurodegenerative Diseases
KW  - Medical Subject Headings::Anatomy::Nervous System::Neurons
TI  - Increased mitochondrial calcium levels associated with neuronal death in a mouse model of Alzheimer's disease
TY  - research article
ER  -