TY  - JOUR
AU  - Prados, María E
AU  - Correa-Sáez, Alejandro
AU  - Unciti-Broceta, Juan D
AU  - Garrido-Rodríguez, Martín
AU  - Jimenez-Jimenez, Carla
AU  - Mazzone, Massimiliano
AU  - Minassi, Alberto
AU  - Appendino, Giovanni
AU  - Calzado, Marco A
AU  - Muñoz, Eduardo
PY  - 2021
DO  - 10.1007/s13311-021-01089-4
UR  - https://hdl.handle.net/10668/25785
T2  - Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics
AB  - Huntington's disease (HD) is a neurodegenerative disorder characterized by unwanted choreatic movements, behavioral and psychiatric disturbances, and dementia. The activation of the hypoxic response pathway through the pharmacological inhibition of...
LA  - en
KW  - Betulinic acid
KW  - Hypoxia-inducing factor
KW  - Neuroprotection
KW  - Prolyl-hydroxylases
KW  - Protein phosphatase A2
KW  - Animals
KW  - Corpus Striatum
KW  - HEK293 Cells
KW  - Humans
KW  - Hypoxia-Inducible Factor 1, alpha Subunit
KW  - Hypoxia-Inducible Factor-Proline Dioxygenases
KW  - Mice
KW  - Mice, Inbred C57BL
KW  - NIH 3T3 Cells
KW  - Neuroprotective Agents
KW  - Nitro Compounds
KW  - Pentacyclic Triterpenes
KW  - Phosphorylation
KW  - Propionates
KW  - Protein Phosphatase 2
KW  - Betulinic Acid
TI  - Betulinic Acid Hydroxamate is Neuroprotective and Induces Protein Phosphatase 2A-Dependent HIF-1α Stabilization and Post-transcriptional Dephosphorylation of Prolyl Hydrolase 2.
TY  - research article
VL  - 18
ER  -