TY - JOUR AU - Rodrigues-Santos, Paulo AU - Lopez-Sejas, Nelson AU - Almeida, Jani Sofia AU - Ruzičkova, Lenka AU - Couceiro, Patricia AU - Alves, Vera AU - Campos, Carmen AU - Alonso, Corona AU - Tarazona, Raquel AU - Freitas-Tavares, Paulo AU - Solana, Rafael AU - Santos-Rosa, Manuel PY - 2018 DO - 10.3389/fimmu.2018.02587 UR - http://hdl.handle.net/10668/13257 T2 - Frontiers in immunology AB - Natural killer (NK) cells are a very important component of the innate immune response involved in the lysis of virus infected and tumor cells. Aging has a profound impact in the frequency, phenotype and function of NK cells. Chronic Myeloid Leukemia... LA - en PB - Frontiers Research Foundation KW - CML KW - NK cell subsets KW - NK receptors KW - Activation markers KW - Aging KW - Cytokines KW - Differentiation markers KW - Tyrosine kinase inhibitors KW - Adult KW - Age factors KW - Aged KW - Aged, 80 and over KW - Aging KW - Antineoplastic agents KW - Cell differentiation KW - Female KW - Genes, abl KW - Humans KW - K562 cells KW - Killer cells, natural KW - Leukemia, myelogenous, chronic, BCR-ABL positive KW - Lymphocyte activation KW - Male KW - Middle aged KW - Protein kinase inhibitors KW - Treatment outcome TI - Effect of Age on NK Cell Compartment in Chronic Myeloid Leukemia Patients Treated With Tyrosine Kinase Inhibitors. TY - research article VL - 9 ER -