TY - JOUR AU - Rodriguez-Hernandez, Maria A AU - Chapresto-Garzon, Raquel AU - Cadenas, Miryam AU - Navarro-Villaran, Elena AU - Negrete, Maria AU - Gomez-Bravo, Miguel A AU - Victor, Victor M AU - Padillo, Francisco J AU - Muntane, Jordi PY - 2020 DO - 10.1038/s41419-020-2558-1 UR - http://hdl.handle.net/10668/15529 T2 - Cell death & disease AB - Sorafenib and Regorafenib are the recommended first- and second-line therapies in patients with advanced hepatocellular carcinoma (HCC). Lenvatinib and Cabozantinib have shown non-inferior antitumoral activities compared with the corresponding... LA - en PB - Nature Publishing Group KW - Predictive markers KW - Liver cancer KW - Adult KW - Anilides KW - Apoptosis KW - Cell Culture Techniques KW - Cell Differentiation KW - Cell Proliferation KW - Cell Respiration KW - Female KW - Hep G2 Cells KW - Hepatocytes KW - Humans KW - Liver Neoplasms KW - Male KW - Mitochondria KW - Oxygen Consumption KW - Phenylurea Compounds KW - Protein Kinase Inhibitors KW - Pyridines KW - Quinolines KW - Sorafenib KW - Spheroids, Cellular KW - Tumor Suppressor Protein p53 TI - Differential effectiveness of tyrosine kinase inhibitors in 2D/3D culture according to cell differentiation, p53 status and mitochondrial respiration in liver cancer cells. TY - research article VL - 11 ER -