RT Journal Article
T1 Risk of fetal loss after chorionic villus sampling in twin pregnancy derived from propensity score matching analysis
A1 Gil, M. M.
A1 Rodriguez-Fernandez, M.
A1 Elger, T.
A1 Akolekar, R.
A1 Syngelaki, A.
A1 De Paco Matallana, C.
A1 Molina, F. S.
A1 Gallardo Arocena, M.
A1 Chaveeva, P.
A1 Persico, N.
A1 Accurti, V
A1 Kagan, K. O.
A1 Prodan, N.
A1 Cruz, J.
A1 Nicolaides, K. H.
K1 adverse pregnancy outcome
K1 chorionic villus sampling
K1 CVS
K1 first-trimester screening
K1 invasive procedure
K1 invasive testing
K1 miscarriage
K1 pregnancy complications
K1 prenatal diagnosis
K1 Nuchal translucency
K1 Prediction
K1 Model
AB Objective To estimate the risk of fetal loss associated with chorionic villus sampling (CVS) in twin pregnancy, using propensity score analysis. Methods This was a multicenter cohort study of women with twin pregnancy undergoing ultrasound examination at 11-13 weeks' gestation, performed in eight fetal medicine units in which the leadership were trained at the Harris Birthright Research Centre for Fetal Medicine in London, UK, and in which the protocols for screening, invasive testing and pregnancy management are similar. The risk of death of at least one fetus was compared between pregnancies that had and those that did not have CVS, after propensity score matching (1:1 ratio). This procedure created two comparable groups by balancing the maternal and pregnancy characteristics that lead to CVS being performed, similar to how randomization operates in a randomized clinical trial. Results The study population of 8581 twin pregnancies included 445 that had CVS. Death of one or two fetuses at any stage during pregnancy occurred in 11.5% (51/445) of pregnancies in the CVS group and in 6.3% (515/8136) in the non-CVS group (P
PB Wiley
SN 0960-7692
YR 2022
FD 2022-01-13
LK https://hdl.handle.net/10668/26017
UL https://hdl.handle.net/10668/26017
LA en
DS RISalud
RD Apr 7, 2025